PA1-30779 detects SIRP alpha from human, mouse, and rat samples.
PA1-30779 has been successfully used in Western blot applications. Positive control of THP-1 whole cell lysate suggested.
The PA1-30779 immunogen is a peptide corresponding to amino acids 487 to 503 of human SIRPa1. The sequences of immunogenicpeptide differ from those of mouse, rat and bovine by one amino acid.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.
SIRPs are heterophilic adhesive membrane glycoproteins with three extracellular Ig like domains and a cytoplasmic domain with two immunoreceptor with tyrosine based inhibition motifs that can interact with src homology 2 domain containing phosphatases.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: BIT; Brain Ig-like molecule with tyrosine-based activation motifs; Brain immunoglobulin like protein with tyrosine - based activation motifs; brain immunological-like with tyrosine-based motifs; brain-immunoglobulin-like molecule with tyrosine-based activation motifs; CD172 antigen-like family member A; CD172a; Inhibitory receptor SHPS-1; Macrophage fusion receptor; Macrophage membrane protein MFP150; mSIRP-alpha1; MyD-1 antigen; p84; Protein tyrosine phosphatase non-receptor type substrate 1 (SHP substrate 1); protein tyrosine phosphatase, non-receptor type substrate 1; Protein tyrosine phosphatase, non-receptor type substrate 1 (SHP substrate 1); SHP substrate 1; SHPS1; Signal Regulatory Protein Alpha; signal-regulatory protein alpha; Signal-regulatory protein alpha-1; Signal-regulatory protein alpha-2; Signal-regulatory protein alpha-3; Sirp-alpha-1; Sirp-alpha-2; Sirp-alpha-3; tyrosine phosphatase SHP substrate 1; Tyrosine-protein phosphatase non-receptor type substrate 1
Gene Aliases: AI835480; BIT; CD172A; MFR; MYD-1; MYD1; P84; PTPNS1; SHP-1; SHPS-1; SHPS1; SIRP; SIRPA