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|Tested species reactivity||Human, Mouse, Rat|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Peptide corresponding to amino acids 487 to 503 ofhuman SIRPa1. The sequences of immunogenicpeptide differ from those of mouse, rat and bovine by one amino acid.|
|Contains||0.02% sodium azide|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:1000-1:2000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA1-30779 detects SIRP alpha from human, mouse, and rat samples.
PA1-30779 has been successfully used in Western blot applications. Positive control of THP-1 whole cell lysate suggested.
The PA1-30779 immunogen is a peptide corresponding to amino acids 487 to 503 of human SIRPa1. The sequences of immunogenicpeptide differ from those of mouse, rat and bovine by one amino acid.
SIRPs are heterophilic adhesive membrane glycoproteins with three extracellular Ig like domains and a cytoplasmic domain with two immunoreceptor with tyrosine based inhibition motifs that can interact with src homology 2 domain containing phosphatases.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
BIT; brain Ig-like molecule with tyrosine-based activation motifs; Brain immunoglobulin like protein with tyrosine - based activation motifs; brain immunological-like with tyrosine-based motifs; brain-immunoglobulin-like molecule with tyrosine-based activation motifs; CD172 antigen-like family member A; inhibitory receptor SHPS-1; macrophage fusion receptor; macrophage membrane protein MFP150; mSIRP-alpha1; myD-1 antigen; Protein tyrosine phosphatase non-receptor type substrate 1 (SHP substrate 1); protein tyrosine phosphatase, non-receptor type substrate 1; Protein tyrosine phosphatase, non-receptor type substrate 1 (SHP substrate 1); SHP substrate 1; SHPS1; Signal Regulatory Protein Alpha; signal-regulatory protein alpha; signal-regulatory protein alpha-1; sirp-alpha-1; tyrosine phosphatase SHP substrate 1; tyrosine-protein phosphatase non-receptor type substrate 1
AI835480; BIT; CD172A; MFR; MYD-1; MYD1; P84; PTPNS1; SHP-1; SHPS-1; SHPS1; SIRP; SIRPA