Product References
Immunoexpression of SIRT1, 6, and 7 in oral leukoplakia and oral squamous cell carcinoma.
Odontology
Sripodok P,Saito H,Kouketsu A,Takahashi T,Kumamoto H
Mon Jan 01 00:00:00 UTC 2024
Xiaojianzhong decoction prevents gastric precancerous lesions in rats by inhibiting autophagy and glycolysis in gastric mucosal cells.
World journal of gastrointestinal oncology
Zhang JX,Bao SC,Chen J,Chen T,Wei HL,Zhou XY,Li JT,Yan SG
Wed Mar 15 00:00:00 UTC 2023
SIRT6 attenuates LPS-induced inflammation and apoptosis of lung epithelial cells in acute lung injury through ACE2/STAT3/PIM1 signaling.
Immunity, inflammation and disease
Yang J,Chen X
Wed Mar 01 00:00:00 UTC 2023
Inhibition of the AKT1/mTOR pathway through SIRT6 over expression downregulated the expression of programmed death-ligand 1 and prolonged overall survival in lung adenocarcinoma.
Annals of translational medicine
Yuan ZF,Lin YD,Wu GS,Li L,Yang JP,Zhang JW
Sun Jan 15 00:00:00 UTC 2023
Metrnl Alleviates Lipid Accumulation by Modulating Mitochondrial Homeostasis in Diabetic Nephropathy.
Diabetes
Zhou Y,Liu L,Jin B,Wu Y,Xu L,Chang X,Hu L,Wang G,Huang Y,Song L,Zhang T,Wang Y,Xiao Y,Zhang F,Shi M,Liu L,Wang T,Yan R,Guo B
Mon May 01 00:00:00 UTC 2023
Melatonin inhibits ferroptosis and delays age-related cataract by regulating SIRT6/p-Nrf2/GPX4 and SIRT6/NCOA4/FTH1 pathways.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Mi Y,Wei C,Sun L,Liu H,Zhang J,Luo J,Yu X,He J,Ge H,Liu P
Sun Jan 01 00:00:00 UTC 2023
Melatonin inhibits ferroptosis and delays age-related cataract by regulating SIRT6/p-Nrf2/GPX4 and SIRT6/NCOA4/FTH1 pathways.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Mi Y,Wei C,Sun L,Liu H,Zhang J,Luo J,Yu X,He J,Ge H,Liu P
Sun Jan 01 00:00:00 UTC 2023
N6-methyladenosine of Spi2a attenuates inflammation and sepsis-associated myocardial dysfunction in mice.
Nature communications
Wang X,Ding Y,Li R,Zhang R,Ge X,Gao R,Wang M,Huang Y,Zhang F,Zhao B,Liao W,Du J
Thu Mar 02 00:00:00 UTC 2023
Caffeic Acid Phenethyl Ester Suppresses Oxidative Stress and Regulates M1/M2 Microglia Polarization via Sirt6/Nrf2 Pathway to Mitigate Cognitive Impairment in Aged Mice following Anesthesia and Surgery.
Antioxidants (Basel, Switzerland)
Wang Y,Cai Z,Zhan G,Li X,Li S,Wang X,Li S,Luo A
Mon Mar 13 00:00:00 UTC 2023
Hepatic SIRT6 Modulates Transcriptional Activities of FXR to Alleviate Acetaminophen-induced Hepatotoxicity.
Cellular and molecular gastroenterology and hepatology
Liu C,Pan Z,Wu Z,Tang K,Zhong Y,Chen Y,Xiao X,Guo J,Duan S,Cui T,Zhong G,Yang Z,Zhong C,Lin S,Gao Y
Mon Jul 25 00:00:00 UTC 2022
SIRT6 Activator UBCS039 Inhibits Thioacetamide-Induced Hepatic Injury In Vitro and In Vivo.
Frontiers in pharmacology
Jiao F,Zhang Z,Hu H,Zhang Y,Xiong Y
Wed Nov 01 00:00:00 UTC 2023
SIRT6 Activator UBCS039 Inhibits Thioacetamide-Induced Hepatic Injury In Vitro and In Vivo.
Frontiers in pharmacology
Jiao F,Zhang Z,Hu H,Zhang Y,Xiong Y
Wed Nov 01 00:00:00 UTC 2023
Selective transportation and energy homeostasis regulation of dietary advanced glycation end-products in human intestinal Caco-2 cells.
Food chemistry
Wu Y,Zong M,Zhang Z,Wu Y,Li L,Zhang X,Wu H,Li B
Sat Oct 15 00:00:00 UTC 2022
Selective transportation and energy homeostasis regulation of dietary advanced glycation end-products in human intestinal Caco-2 cells.
Food chemistry
Wu Y,Zong M,Zhang Z,Wu Y,Li L,Zhang X,Wu H,Li B
Sat Oct 15 00:00:00 UTC 2022
A new FGF1 variant protects against adriamycin-induced cardiotoxicity via modulating p53 activity.
Redox biology
Xiao M,Tang Y,Wang J,Lu G,Niu J,Wang J,Li J,Liu Q,Wang Z,Huang Z,Guo Y,Gao T,Zhang X,Yue S,Gu J
Tue Feb 01 00:00:00 UTC 2022
Reduction of H3K27cr Modification During DNA Damage in Colon Cancer.
Frontiers in oncology
Liao M,Chu W,Sun X,Zheng W,Gao S,Li D,Pei D
Tue Aug 09 00:00:00 UTC 2022
Targeting USP47 overcomes tyrosine kinase inhibitor resistance and eradicates leukemia stem/progenitor cells in chronic myelogenous leukemia.
Nature communications
Lei H,Xu HZ,Shan HZ,Liu M,Lu Y,Fang ZX,Jin J,Jing B,Xiao XH,Gao SM,Gao FH,Xia L,Yang L,Liu LG,Wang WW,Liu CX,Tong Y,Wu YZ,Zheng JK,Chen GQ,Zhou L,Wu YL
Mon Jan 04 00:00:00 UTC 2021
Total Sesquiterpene Glycosides from Loquat Leaves Ameliorate HFD-Induced Insulin Resistance by Modulating IRS-1/GLUT4, TRPV1, and SIRT6/Nrf2 Signaling Pathways.
Oxidative medicine and cellular longevity
Wu R,Jian T,Ding X,Lv H,Meng X,Ren B,Li J,Chen J,Li W
Thu Feb 17 00:00:00 UTC 2022
Sirtuin 6 supra-physiological overexpression in hypothalamic pro-opiomelanocortin neurons promotes obesity via the hypothalamus-adipose axis.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Tang Q,Liu Q,Yang X,Wu T,Huang C,Zhang J,Zhang Z,Zhang G,Zhao Y,Zhou J,Huang H,Xia Y,Yan J,Li Y,He J
Mon Mar 01 00:00:00 UTC 2021
Bioinformatics Analysis of the SIRT Family Members and Assessment of Their Potential Clinical Value.
OncoTargets and therapy
Liu M,Yu J,Jin H,Wang S,Ding J,Xing H,He S,Zeng Y
Fri Apr 22 00:00:00 UTC 2022
Bone marrow mesenchymal stem cell exosomes suppress phosphate-induced aortic calcification via SIRT6-HMGB1 deacetylation.
Stem cell research & therapy
Wei W,Guo X,Gu L,Jia J,Yang M,Yuan W,Rong S
Tue Apr 13 00:00:00 UTC 2021
Bone marrow mesenchymal stem cell exosomes suppress phosphate-induced aortic calcification via SIRT6-HMGB1 deacetylation.
Stem cell research & therapy
Wei W,Guo X,Gu L,Jia J,Yang M,Yuan W,Rong S
Tue Apr 13 00:00:00 UTC 2021
α-Hederin inhibits the growth of lung cancer A549 cells in vitro and in vivo by decreasing SIRT6 dependent glycolysis.
Pharmaceutical biology
Fang C,Liu Y,Chen L,Luo Y,Cui Y,Zhang N,Liu P,Zhou M,Xie Y
Wed Dec 01 00:00:00 UTC 2021
α-Hederin inhibits the growth of lung cancer A549 cells in vitro and in vivo by decreasing SIRT6 dependent glycolysis.
Pharmaceutical biology
Fang C,Liu Y,Chen L,Luo Y,Cui Y,Zhang N,Liu P,Zhou M,Xie Y
Wed Dec 01 00:00:00 UTC 2021
Kisspeptin-10 Maintains the Activation of the mTOR Signaling Pathway by Inhibiting SIRT6 to Promote the Synthesis of Milk in Bovine Mammary Epithelial Cells.
Journal of agricultural and food chemistry
Cao Y,Hu G,Zhang Q,Ma L,Wang J,Li W,Ge Y,Cheng J,Yang Z,Fu S,Liu J
Wed Apr 14 00:00:00 UTC 2021
Exercise ameliorates insulin resistance and improves SIRT6-mediated insulin signaling transduction in liver of obese rats.
Canadian journal of physiology and pharmacology
Zhang Y,Yang Z,Xu Z,Wan J,Hua T,Sun Q
Sat May 01 00:00:00 UTC 2021
Age-related changes of human serum Sirtuin6 in adults.
BMC geriatrics
Zhao Y,Bai X,Jia X,Lu Y,Cheng W,Shu M,Zhu Y,Zhu L,Wang L,Shu Y,Song Y,Jin S
Wed Aug 04 00:00:00 UTC 2021
Influence of psychostimulants and opioids on epigenetic modification of class III histone deacetylase (HDAC)-sirtuins in glial cells.
Scientific reports
Sivalingam K,Doke M,Khan MA,Samikkannu T
Fri Oct 29 00:00:00 UTC 2021
The effect of high glucose on the biological characteristics of nucleus pulposus-derived mesenchymal stem cells.
Cell biochemistry and function
Liu Y,Li Y,Nan LP,Wang F,Zhou SF,Wang JC,Feng XM,Zhang L
Sun Mar 01 00:00:00 UTC 2020
Associations of sirtuins with clinicopathological variables and prognosis in human ovarian cancer.
Oncology letters
He Q,Chen K,Ye R,Dai N,Guo P,Wang L
Wed Apr 01 00:00:00 UTC 2020
The SIRT6-Autophagy-Warburg Effect Axis in Papillary Thyroid Cancer.
Frontiers in oncology
Yang Z,Huang R,Wei X,Yu W,Min Z,Ye M
Thu Oct 01 00:00:00 UTC 2020
The effect of intervertebral disc degenerative change on biological characteristics of nucleus pulposus mesenchymal stem cell: an in vitro study in rats.
Connective tissue research
Liu Y,Li Y,Huang ZN,Wang ZY,Nan LP,Wang F,Zhou SF,Wang JC,Feng XM,Zhang L
Mon Jul 01 00:00:00 UTC 2019
Comprehensive Analysis of Expression and Prognostic Value of Sirtuins in Ovarian Cancer.
Frontiers in genetics
Sun X,Wang S,Li Q
Thu Oct 01 00:00:00 UTC 2020
Cordycepin prevents radiation ulcer by inhibiting cell senescence via NRF2 and AMPK in rodents.
Nature communications
Wang Z,Chen Z,Jiang Z,Luo P,Liu L,Huang Y,Wang H,Wang Y,Long L,Tan X,Liu D,Jin T,Wang Y,Wang Y,Liao F,Zhang C,Chen L,Gan Y,Liu Y,Yang F,Huang C,Miao H,Chen J,Cheng T,Fu X,Shi C
Mon Jun 10 00:00:00 UTC 2019
SIRT6/HIF-1α axis promotes papillary thyroid cancer progression by inducing epithelial-mesenchymal transition.
Cancer cell international
Yang Z,Yu W,Huang R,Ye M,Min Z
Wed Aug 23 00:00:00 UTC 2023
SIRT6/HIF-1α axis promotes papillary thyroid cancer progression by inducing epithelial-mesenchymal transition.
Cancer cell international
Yang Z,Yu W,Huang R,Ye M,Min Z
Wed Aug 23 00:00:00 UTC 2023
SIRT6/HIF-1α axis promotes papillary thyroid cancer progression by inducing epithelial-mesenchymal transition.
Cancer cell international
Yang Z,Yu W,Huang R,Ye M,Min Z
Wed Aug 23 00:00:00 UTC 2023
SIRT6 promotes the Warburg effect of papillary thyroid cancer cell BCPAP through reactive oxygen species.
OncoTargets and therapy
Yu W,Yang Z,Huang R,Min Z,Ye M
Thu Oct 01 00:00:00 UTC 2020
Sirtuin-mediated deacetylation of hnRNP A1 suppresses glycolysis and growth in hepatocellular carcinoma.
Oncogene
Yang H,Zhu R,Zhao X,Liu L,Zhou Z,Zhao L,Liang B,Ma W,Zhao J,Liu J,Huang G
Sat Jun 01 00:00:00 UTC 2019
Sirtuin-mediated deacetylation of hnRNP A1 suppresses glycolysis and growth in hepatocellular carcinoma.
Oncogene
Yang H,Zhu R,Zhao X,Liu L,Zhou Z,Zhao L,Liang B,Ma W,Zhao J,Liu J,Huang G
Sat Jun 01 00:00:00 UTC 2019
Relationship between senescence in macaques and bone marrow mesenchymal stem cells and the molecular mechanism.
Aging
Pan XH,Chen YH,Yang YK,Zhang XJ,Lin QK,Li ZA,Cai XM,Pang RQ,Zhu XQ,Ruan GP
Wed Jan 23 00:00:00 UTC 2019
Downregulation of SIRT6 by miR-34c-5p is associated with poor prognosis and promotes colon cancer proliferation through inhibiting apoptosis via the JAK2/STAT3 signaling pathway.
International journal of oncology
Li N,Mao D,Cao Y,Li H,Ren F,Li K
Tue May 01 00:00:00 UTC 2018
Downregulation of SIRT6 by miR-34c-5p is associated with poor prognosis and promotes colon cancer proliferation through inhibiting apoptosis via the JAK2/STAT3 signaling pathway.
International journal of oncology
Li N,Mao D,Cao Y,Li H,Ren F,Li K
Tue May 01 00:00:00 UTC 2018
Autophagy activated by SIRT6 regulates Aβ induced inflammatory response in RPEs.
Biochemical and biophysical research communications
Feng Y,Liang J,Zhai Y,Sun J,Wang J,She X,Gu Q,Liu Y,Zhu H,Luo X,Sun X
Mon Feb 19 00:00:00 UTC 2018
Autophagy activated by SIRT6 regulates Aβ induced inflammatory response in RPEs.
Biochemical and biophysical research communications
Feng Y,Liang J,Zhai Y,Sun J,Wang J,She X,Gu Q,Liu Y,Zhu H,Luo X,Sun X
Mon Feb 19 00:00:00 UTC 2018
SIRT6 regulates osteogenic differentiation of rat bone marrow mesenchymal stem cells partially via suppressing the nuclear factor-κB signaling pathway.
Stem cells (Dayton, Ohio)
Sun H,Wu Y,Fu D,Liu Y,Huang C
Tue Jul 01 00:00:00 UTC 2014
SIRT6 regulates osteogenic differentiation of rat bone marrow mesenchymal stem cells partially via suppressing the nuclear factor-κB signaling pathway.
Stem cells (Dayton, Ohio)
Sun H,Wu Y,Fu D,Liu Y,Huang C
Tue Jul 01 00:00:00 UTC 2014
SIRT6 regulates osteogenic differentiation of rat bone marrow mesenchymal stem cells partially via suppressing the nuclear factor-κB signaling pathway.
Stem cells (Dayton, Ohio)
Sun H,Wu Y,Fu D,Liu Y,Huang C
Tue Jul 01 00:00:00 UTC 2014
SIRT6 regulates osteogenic differentiation of rat bone marrow mesenchymal stem cells partially via suppressing the nuclear factor-κB signaling pathway.
Stem cells (Dayton, Ohio)
Sun H,Wu Y,Fu D,Liu Y,Huang C
Tue Jul 01 00:00:00 UTC 2014
The effect of SIRT6 on the odontoblastic potential of human dental pulp cells.
Journal of endodontics
Sun HL,Wu YR,Huang C,Wang JW,Fu DJ,Liu YC
Sat Mar 01 00:00:00 UTC 2014
The effect of SIRT6 on the odontoblastic potential of human dental pulp cells.
Journal of endodontics
Sun HL,Wu YR,Huang C,Wang JW,Fu DJ,Liu YC
Sat Mar 01 00:00:00 UTC 2014
The effect of SIRT6 on the odontoblastic potential of human dental pulp cells.
Journal of endodontics
Sun HL,Wu YR,Huang C,Wang JW,Fu DJ,Liu YC
Sat Mar 01 00:00:00 UTC 2014
The effect of SIRT6 on the odontoblastic potential of human dental pulp cells.
Journal of endodontics
Sun HL,Wu YR,Huang C,Wang JW,Fu DJ,Liu YC
Sat Mar 01 00:00:00 UTC 2014