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Search Thermo Fisher Scientific
Applications | Tested Dilution | Publications |
---|---|---|
Western Blot (WB) |
1:500-1:2,000 | View 2 publications 2 publications |
Immunohistochemistry (IHC) |
- | View 2 publications 2 publications |
Immunohistochemistry (Paraffin) (IHC (P)) |
1:50-1:200 | - |
Immunocytochemistry (ICC/IF) |
- | View 2 publications 2 publications |
Product Specifications | |
---|---|
Species Reactivity |
Human, Mouse, Rat |
Published species |
Human, Mouse, Rat |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
SIRT6 Fusion Protein Ag4469 (1-328 aa encoded by BC028220) |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
0.29 mg/mL |
Purification |
Antigen affinity chromatography |
Storage buffer |
PBS, pH 7.3, with 50% glycerol |
Contains |
0.02% sodium azide |
Storage conditions |
-20°C |
This antibody is a rabbit polyclonal antibody raised against full length human SIRT6 antigen.
Immunogen sequence: MSVNYAAGL SPYADKGKCG LPEIFDPPEE LERKVWELAR LVWQSSNVVF HTGAGISTAS GIPDFRGPHG VWTMEERGLA PKFDTTFESA RPTQTHMALV QLERVGLLRF LVSQNVDGLH VRSGFPRDKL AELHGNMFVE ECAKCKTQYV RDTVVGTMGL KATGRLCTVA KARGLRACRN ADLSITLGTS LQIRPSGNLP LATKRRGGRL VIVNLQPTKH DRHADLRIHG YVDEVMTRLM KHLGLEIPAW DGPRVLERAL PPLPRPPTPK LEPKEESPTR INGSIPAGPK QEPCAQHNGS EPASPKRERP TSPAPHRPPK RVKAKAVPS (1-328 aa encoded by BC028220 )
Sirtuins regulate epigenetic gene silencing. SIRT6 (Mono-ADP-ribosyltransferase sirtuin-6), a mouse Sir2 homolog, is a chromatin-associated nuclear ADP-ribosyltransferase protein. It appears to be involved in DNA repair and may also play a role in human aging.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: hSIRT6; mSIRT6; NAD-dependent deacetylase sirtuin-6; NAD-dependent protein deacetylase sirtuin-6; NAD-dependent protein deacylase sirtuin-6; Protein mono-ADP-ribosyltransferase sirtuin-6; Regulatory protein SIR2 homolog 6; SIR2; SIR2 like 6; SIR2-like protein 6; sir2-related protein type 6; sirtuin type 6
Gene Aliases: 2810449N18Rik; AI043036; SIR2L6; SIRT6
UniProt ID: (Human) Q8N6T7, (Mouse) P59941
Entrez Gene ID: (Human) 51548, (Mouse) 50721, (Rat) 299638
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