Human SIRT6 shares 95% amino acid (aa) sequence identity with mouse SIRT6.
Reconstitution information: Add 0.2 mL of distilled water will yield a concentration of 500 µg/mL.
Sirtuins regulate epigenetic gene silencing. SIRT6 (Mono-ADP-ribosyltransferase sirtuin-6), a mouse Sir2 homolog, is a chromatin-associated nuclear ADP-ribosyltransferase protein. It appears to be involved in DNA repair and may also play a role in human aging.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 3.5.1.-; NAD-dependent deacetylase sirtuin-6; NAD-dependent protein deacetylase sirtuin-6; Regulatory protein SIR2 homolog 6; SIR2-like protein 6; sir2-related protein type 6; SIR2L6; SIRT6; sirtuin type 6
Gene Aliases: 2810449N18Rik; AI043036; SIR2L6; SIRT6