Applications | Tested Dilution | Publications |
---|---|---|
Western Blot (WB) |
1:500-1:1,000 | - |
ELISA (ELISA) |
1:10,000 | - |
Immunoprecipitation (IP) |
1:50-1:250 | - |
Product Specifications | |
---|---|
Species Reactivity |
Human, Mouse, Rat |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
Synthetic peptide taken within amino acid region 350-400 on mouse SIRT7 protein. |
Conjugate |
FITC |
Excitation/Emission Profile |
View spectra |
Form |
Liquid |
Concentration |
0.5-1.5 mg/mL |
Purification |
Affinity chromatography |
Storage buffer |
proprietary buffer, pH 7.4-7.8, with 30% glycerol, 0.5% BSA |
Contains |
0.02% sodium azide |
Storage conditions |
-20° C, store in dark |
SIRT7 is a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. SIRT7 is included in class IV. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. SIRT7 is included in class IV of the sirtuin family.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: MGC126840; MGC126842; NAD-dependent deacetylase sirtuin-7; NAD-dependent protein deacetylase sirtuin-7; NAD-dependent protein deacylase sirtuin-7; Regulatory protein SIR2 homolog 7; silent mating type information regulation 2, S.cerevisiae, homolog 7; SIR2-like protein 7; sir2-related protein type 7; sirtuin type 7
Gene Aliases: SIR2L7; SIRT7
UniProt ID: (Human) Q9NRC8, (Mouse) Q8BKJ9, (Rat) B2RZ55
Entrez Gene ID: (Human) 51547, (Mouse) 209011, (Rat) 303745
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