Peptide sequence: SEEEFSPPQS PDQNSVLLLQ GNMGHARSSN YSLPGLTASQ PSHGLQTHQH
Sequence homology: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 93%; Rat: 100%; Sheep: 100%
The protein encoded by this gene is a homeobox protein that is similar to the Drosophila 'sine oculis' gene product. This gene is found in a cluster of related genes on chromosome 14 and is thought to be involved in limb development. Defects in this gene are a cause of autosomal dominant deafness type 23 (DFNA23) and branchiootic syndrome type 3 (BOS3). [provided by RefSeq, Jul 2008].
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Protein Aliases: BOS3; DFNA23; Homeobox protein SIX1; Sine oculis homeobox homolog 1; sine oculis-related homeobox 1 homolog; SIX homeobox 1
Gene Aliases: BB138287; BOS3; DFNA23; SIX1; TIP39