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Proteintech
SIX2 Polyclonal Antibody
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Product Details
11562-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Human,
Mouse,
Pig,
Rat,
Reptile
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
SIX2 Fusion Protein Ag2124 (1-291 aa encoded by BC024033)
Conjugate
Form
Liquid
Concentration
0.52 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
This antibody is a rabbit polyclonal antibody raised against full length SIX2 of human origin.
Immunogen sequence: MSMLPTFGF TQEQVACVCE VLQQGGNIER LGRFLWSLPA CEHLHKNESV LKAKAVVAFH RGNFRELYKI LESHQFSPHN HAKLQQLWLK AHYIEAEKLR GRPLGAVGKY RVRRKFPLPR SIWDGEETSY CFKEKSRSVL REWYAHNPYP SPREKRELTE ATGLTTTQVS NWFKNRRQRD RAAEAKEREN NENSNSNSHN PLNGSGKSVL GSSEDEKTPS GTPDHSSSSP ALLLSPPPPG LPSLHSLGHP PGPSAVPVPV PGGGGADPLQ HHHGLQDSIL NPMSANLVDL GS (1-291 aa encoded by BC024033)
Target Information
This gene is a member of the vertebrate gene family which encode proteins homologous to the Drosophila 'sine oculis' homeobox protein. SIX2 is a transcription factor which, like other members of this gene family, may be involved in limb or eye development.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Homeobox protein SIX2; Sine oculis homeobox homolog 2
Gene Aliases: SIX2
UniProt ID: (Human) Q9NPC8
Entrez Gene ID: (Human) 10736
RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
transcription factor activity, sequence-specific DNA binding
transcription factor binding
protein complex binding
homeodomain transcription factor
kidney development
chondrocyte differentiation
mesenchymal to epithelial transition involved in metanephros morphogenesis
transcription from RNA polymerase II promoter
protein import into nucleus
mesodermal cell fate specification
cell proliferation
anatomical structure morphogenesis
anterior/posterior axis specification
cell migration
regulation of ossification
regulation of chondrocyte differentiation
middle ear morphogenesis
negative regulation of cell differentiation
positive regulation of transcription from RNA polymerase II promoter
embryonic digestive tract morphogenesis
embryonic cranial skeleton morphogenesis
nephron development
nephron morphogenesis
mesenchymal stem cell maintenance involved in nephron morphogenesis
mesenchymal cell differentiation involved in kidney development
regulation of branching involved in ureteric bud morphogenesis
mesenchymal stem cell proliferation
positive regulation of chondrocyte proliferation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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