Product References
Six2 Plays an Intrinsic Role in Regulating Proliferation of Mesenchymal Cells in the Developing Palate.
Frontiers in physiology
Okello DO,Iyyanar PPR,Kulyk WM,Smith TM,Lozanoff S,Ji S,Nazarali AJ
Fri Mar 11 00:00:00 EST 2022
Six2 Plays an Intrinsic Role in Regulating Proliferation of Mesenchymal Cells in the Developing Palate.
Frontiers in physiology
Okello DO,Iyyanar PPR,Kulyk WM,Smith TM,Lozanoff S,Ji S,Nazarali AJ
Fri Mar 11 00:00:00 EST 2022
Effect of Hypoxia on the Differentiation and the Self-Renewal of Metanephrogenic Mesenchymal Stem Cells.
Stem cells international
Liu S,Song N,He J,Yu X,Guo J,Jiao X,Ding X,Teng J
Wed Sep 30 00:00:00 EDT 2020
Effect of Hypoxia on the Differentiation and the Self-Renewal of Metanephrogenic Mesenchymal Stem Cells.
Stem cells international
Liu S,Song N,He J,Yu X,Guo J,Jiao X,Ding X,Teng J
Wed Sep 30 00:00:00 EDT 2020
Disabling of nephrogenesis in porcine embryos via CRISPR/Cas9-mediated SIX1 and SIX4 gene targeting.
Xenotransplantation
Wang J,Liu M,Zhao L,Li Y,Zhang M,Jin Y,Xiong Q,Liu X,Zhang L,Jiang H,Chen Q,Wang C,You Z,Yang H,Cao C,Dai Y,Li R
Wed May 01 00:00:00 EDT 2019
Loss-of-function mutations in KIF14 cause severe microcephaly and kidney development defects in humans and zebrafish.
Human molecular genetics
Reilly ML,Stokman MF,Magry V,Jeanpierre C,Alves M,Paydar M,Hellinga J,Delous M,Pouly D,Failler M,Martinovic J,Loeuillet L,Leroy B,Tantau J,Roume J,Gregory-Evans CY,Shan X,Filges I,Allingham JS,Kwok BH,Saunier S,Giles RH,Benmerah A
Fri Mar 01 00:00:00 EST 2019
Lin28 and let-7 regulate the timing of cessation of murine nephrogenesis.
Nature communications
Yermalovich AV,Osborne JK,Sousa P,Han A,Kinney MA,Chen MJ,Robinton DA,Montie H,Pearson DS,Wilson SB,Combes AN,Little MH,Daley GQ
Fri Jan 11 00:00:00 EST 2019
Lin28 and let-7 regulate the timing of cessation of murine nephrogenesis.
Nature communications
Yermalovich AV,Osborne JK,Sousa P,Han A,Kinney MA,Chen MJ,Robinton DA,Montie H,Pearson DS,Wilson SB,Combes AN,Little MH,Daley GQ
Fri Jan 11 00:00:00 EST 2019
DNA Methyltransferase 1 Controls Nephron Progenitor Cell Renewal and Differentiation.
Journal of the American Society of Nephrology : JASN
Wanner N,Vornweg J,Combes A,Wilson S,Plappert J,Rafflenbeul G,Puelles VG,Rahman RU,Liwinski T,Lindner S,Grahammer F,Kretz O,Wlodek ME,Romano T,Moritz KM,Boerries M,Busch H,Bonn S,Little MH,Bechtel-Walz W,Huber TB
Tue Jan 01 00:00:00 EST 2019
Ex vivo live cell tracking in kidney organoids using light sheet fluorescence microscopy.
PloS one
Held M,Santeramo I,Wilm B,Murray P,Lévy R
Mon Dec 31 00:00:00 EST 2018
Wnt11 directs nephron progenitor polarity and motile behavior ultimately determining nephron endowment.
eLife
O'Brien LL,Combes AN,Short KM,Lindström NO,Whitney PH,Cullen-McEwen LA,Ju A,Abdelhalim A,Michos O,Bertram JF,Smyth IM,Little MH,McMahon AP
Wed Dec 05 00:00:00 EST 2018
Maternal malnourishment induced upregulation of fetuin-B blunts nephrogenesis in the low birth weight neonate.
Developmental biology
Rabadi MM,Abdulmahdi W,Nesi L,Jules E,Marghani Y,Sheinin E,Tilzer J,Gupta S,Chen S,Cassimatis ND,Lipphardt M,Kozlowski PB,Ratliff BB
Thu Nov 01 00:00:00 EDT 2018
Gulo regulates the proliferation, apoptosis and mesenchymal-to-epithelial transformation of metanephric mesenchyme cells via inhibiting Six2.
Biochemical and biophysical research communications
He Q,Chen L,Liu Y,Wu Y,Ni D,Liu J,Hu Y,Gu Y,Xie Y,Zhou Q,Li Q
Fri Oct 12 00:00:00 EDT 2018
Six2 is negatively correlated with good prognosis and decreases 5-FU sensitivity via suppressing E-cadherin expression in hepatocellular carcinoma cells.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Li JW,Huang CZ,Li JH,Yuan JH,Chen QH,Zhang WF,Xu ZS,Liu YP,Li Y,Zhan MX,Lu LG
Wed Aug 01 00:00:00 EDT 2018
Six2 is negatively correlated with good prognosis and decreases 5-FU sensitivity via suppressing E-cadherin expression in hepatocellular carcinoma cells.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Li JW,Huang CZ,Li JH,Yuan JH,Chen QH,Zhang WF,Xu ZS,Liu YP,Li Y,Zhan MX,Lu LG
Wed Aug 01 00:00:00 EDT 2018
Branching morphogenesis in the developing kidney is not impacted by nephron formation or integration.
eLife
Short KM,Combes AN,Lisnyak V,Lefevre JG,Jones LK,Little MH,Hamilton NA,Smyth IM
Tue Jul 31 00:00:00 EDT 2018
EED, a member of the polycomb group, is required for nephron differentiation and the maintenance of nephron progenitor cells.
Development (Cambridge, England)
Zhang L,Ettou S,Khalid M,Taglienti M,Jain D,Jung YL,Seager C,Liu Y,Ng KH,Park PJ,Kreidberg JA
Wed Jul 18 00:00:00 EDT 2018
Hedgehog-GLI signaling in Foxd1-positive stromal cells promotes murine nephrogenesis via TGFβ signaling.
Development (Cambridge, England)
Rowan CJ,Li W,Martirosyan H,Erwood S,Hu D,Kim YK,Sheybani-Deloui S,Mulder J,Blake J,Chen L,Rosenblum ND
Mon Jul 09 00:00:00 EDT 2018
An optimal serum-free defined condition for in vitro culture of kidney organoids.
Biochemical and biophysical research communications
Nishikawa M,Kimura H,Yanagawa N,Hamon M,Hauser P,Zhao L,Jo OD,Yanagawa N
Mon Jul 02 00:00:00 EDT 2018
Centrosome amplification disrupts renal development and causes cystogenesis.
The Journal of cell biology
Dionne LK,Shim K,Hoshi M,Cheng T,Wang J,Marthiens V,Knoten A,Basto R,Jain S,Mahjoub MR
Mon Jul 02 00:00:00 EDT 2018
Reduced Abd-B Hox function during kidney development results in lineage infidelity.
Developmental biology
Magella B,Mahoney R,Adam M,Potter SS
Fri Jun 15 00:00:00 EDT 2018
Histone deacetylases 1 and 2 regulate the transcriptional programs of nephron progenitors and renal vesicles.
Development (Cambridge, England)
Liu H,Chen S,Yao X,Li Y,Chen CH,Liu J,Saifudeen Z,El-Dahr SS
Fri May 18 00:00:00 EDT 2018
Histone deacetylases 1 and 2 regulate the transcriptional programs of nephron progenitors and renal vesicles.
Development (Cambridge, England)
Liu H,Chen S,Yao X,Li Y,Chen CH,Liu J,Saifudeen Z,El-Dahr SS
Fri May 18 00:00:00 EDT 2018
Optimal route of diphtheria toxin administration to eliminate native nephron progenitor cells in vivo for kidney regeneration.
Biochemical and biophysical research communications
Fukunaga S,Yamanaka S,Fujimoto T,Tajiri S,Uchiyama T,Matsumoto K,Ito T,Tanabe K,Yokoo T
Mon Feb 19 00:00:00 EST 2018
Transcriptional regulatory control of mammalian nephron progenitors revealed by multi-factor cistromic analysis and genetic studies.
PLoS genetics
O'Brien LL,Guo Q,Bahrami-Samani E,Park JS,Hasso SM,Lee YJ,Fang A,Kim AD,Guo J,Hong TM,Peterson KA,Lozanoff S,Raviram R,Ren B,Fogelgren B,Smith AD,Valouev A,McMahon AP
Mon Jan 01 00:00:00 EST 2018
Transcriptional regulatory control of mammalian nephron progenitors revealed by multi-factor cistromic analysis and genetic studies.
PLoS genetics
O'Brien LL,Guo Q,Bahrami-Samani E,Park JS,Hasso SM,Lee YJ,Fang A,Kim AD,Guo J,Hong TM,Peterson KA,Lozanoff S,Raviram R,Ren B,Fogelgren B,Smith AD,Valouev A,McMahon AP
Mon Jan 01 00:00:00 EST 2018
Ectopic Phosphorylated Creb Marks Dedifferentiated Proximal Tubules in Cystic Kidney Disease.
The American journal of pathology
Puri P,Schaefer CM,Bushnell D,Taglienti ME,Kreidberg JA,Yoder BK,Bates CM
Mon Jan 01 00:00:00 EST 2018
In Vivo Target Gene Activation via CRISPR/Cas9-Mediated Trans-epigenetic Modulation.
Cell
Liao HK,Hatanaka F,Araoka T,Reddy P,Wu MZ,Sui Y,Yamauchi T,Sakurai M,O'Keefe DD,Núñez-Delicado E,Guillen P,Campistol JM,Wu CJ,Lu LF,Esteban CR,Izpisua Belmonte JC
Thu Dec 14 00:00:00 EST 2017
Higher-Order Kidney Organogenesis from Pluripotent Stem Cells.
Cell stem cell
Taguchi A,Nishinakamura R
Thu Dec 07 00:00:00 EST 2017
Derivation and characterization of integration-free iPSC line ISRM-UM51 derived from SIX2-positive renal cells isolated from urine of an African male expressing the CYP2D6 *4/*17 variant which confers intermediate drug metabolizing activity.
Stem cell research
Bohndorf M,Ncube A,Spitzhorn LS,Enczmann J,Wruck W,Adjaye J
Fri Dec 01 00:00:00 EST 2017
Refuting the hypothesis that semaphorin-3f/neuropilin-2 exclude blood vessels from the cap mesenchyme in the developing kidney.
Developmental dynamics : an official publication of the American Association of Anatomists
Munro DAD,Hohenstein P,Coate TM,Davies JA
Fri Dec 01 00:00:00 EST 2017
Generation of interspecies limited chimeric nephrons using a conditional nephron progenitor cell replacement system.
Nature communications
Yamanaka S,Tajiri S,Fujimoto T,Matsumoto K,Fukunaga S,Kim BS,Okano HJ,Yokoo T
Thu Nov 23 00:00:00 EST 2017
Myc cooperates with β-catenin to drive gene expression in nephron progenitor cells.
Development (Cambridge, England)
Pan X,Karner CM,Carroll TJ
Wed Nov 15 00:00:00 EST 2017
Mutations in GREB1L Cause Bilateral Kidney Agenesis in Humans and Mice.
American journal of human genetics
De Tomasi L,David P,Humbert C,Silbermann F,Arrondel C,Tores F,Fouquet S,Desgrange A,Niel O,Bole-Feysot C,Nitschké P,Roume J,Cordier MP,Pietrement C,Isidor B,Khau Van Kien P,Gonzales M,Saint-Frison MH,Martinovic J,Novo R,Piard J,Cabrol C,Verma IC,Puri R,Journel H,Aziza J,Gavard L,Said-Menthon MH,Heidet L,Saunier S,Jeanpierre C
Thu Nov 02 00:00:00 EDT 2017
Mutations in GREB1L Cause Bilateral Kidney Agenesis in Humans and Mice.
American journal of human genetics
De Tomasi L,David P,Humbert C,Silbermann F,Arrondel C,Tores F,Fouquet S,Desgrange A,Niel O,Bole-Feysot C,Nitschké P,Roume J,Cordier MP,Pietrement C,Isidor B,Khau Van Kien P,Gonzales M,Saint-Frison MH,Martinovic J,Novo R,Piard J,Cabrol C,Verma IC,Puri R,Journel H,Aziza J,Gavard L,Said-Menthon MH,Heidet L,Saunier S,Jeanpierre C
Thu Nov 02 00:00:00 EDT 2017
Sall4 Is Transiently Expressed in the Caudal Wolffian Duct and the Ureteric Bud, but Dispensable for Kidney Development.
PloS one
Toyoda D,Taguchi A,Chiga M,Ohmori T,Nishinakamura R
Fri Oct 13 00:00:00 EDT 2017
Endothelial Progenitors Exist within the Kidney and Lung Mesenchyme.
PloS one
Sims-Lucas S,Schaefer C,Bushnell D,Ho J,Logar A,Prochownik E,Gittes G,Bates CM
Fri Oct 13 00:00:00 EDT 2017
LIM kinase function and renal growth: Potential role for LIM kinases in fetal programming of kidney development.
Life sciences
Sparrow AJ,Sweetman D,Welham SJM
Sun Oct 01 00:00:00 EDT 2017
Directed Differentiation of Human Induced Pluripotent Stem Cells into Fallopian Tube Epithelium.
Scientific reports
Yucer N,Holzapfel M,Jenkins Vogel T,Lenaeus L,Ornelas L,Laury A,Sareen D,Barrett R,Karlan BY,Svendsen CN
Wed Sep 06 00:00:00 EDT 2017
A Novel Method for Isolation of Pluripotent Stem Cells from Human Umbilical Cord Blood.
Stem cells and development
Monti M,Imberti B,Bianchi N,Pezzotta A,Morigi M,Del Fante C,Redi CA,Perotti C
Fri Sep 01 00:00:00 EDT 2017
Bim gene dosage is critical in modulating nephron progenitor survival in the absence of microRNAs during kidney development.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Cerqueira DM,Bodnar AJ,Phua YL,Freer R,Hemker SL,Walensky LD,Hukriede NA,Ho J
Tue Aug 01 00:00:00 EDT 2017
Acellular Mouse Kidney ECM can be Used as a Three-Dimensional Substrate to Test the Differentiation Potential of Embryonic Stem Cell Derived Renal Progenitors.
Stem cell reviews and reports
Sambi M,Chow T,Whiteley J,Li M,Chua S,Raileanu V,Rogers IM
Tue Aug 01 00:00:00 EDT 2017
BMP7 dose-dependently stimulates proliferation and cadherin-11 expression via ERK and p38 in a murine metanephric mesenchymal cell line.
Physiological reports
Awazu M,Nagata M,Hida M
Tue Aug 01 00:00:00 EDT 2017
Osr1 Interacts Synergistically with Wt1 to Regulate Kidney Organogenesis.
PloS one
Xu J,Liu H,Chai OH,Lan Y,Jiang R
Mon Jul 31 00:00:00 EDT 2017
Osr1 Interacts Synergistically with Wt1 to Regulate Kidney Organogenesis.
PloS one
Xu J,Liu H,Chai OH,Lan Y,Jiang R
Mon Jul 31 00:00:00 EDT 2017
Characterisation of Cultured Mesothelial Cells Derived from the Murine Adult Omentum.
PloS one
Dauleh S,Santeramo I,Fielding C,Ward K,Herrmann A,Murray P,Wilm B
Wed Jul 19 00:00:00 EDT 2017
Evidence of In Vitro Preservation of Human Nephrogenesis at the Single-Cell Level.
Stem cell reports
Pode-Shakked N,Gershon R,Tam G,Omer D,Gnatek Y,Kanter I,Oriel S,Katz G,Harari-Steinberg O,Kalisky T,Dekel B
Tue Jul 11 00:00:00 EDT 2017
Cycles of vascular plexus formation within the nephrogenic zone of the developing mouse kidney.
Scientific reports
Munro DAD,Hohenstein P,Davies JA
Mon Jun 12 00:00:00 EDT 2017
Repression of Interstitial Identity in Nephron Progenitor Cells by Pax2 Establishes the Nephron-Interstitium Boundary during Kidney Development.
Developmental cell
Naiman N,Fujioka K,Fujino M,Valerius MT,Potter SS,McMahon AP,Kobayashi A
Mon May 22 00:00:00 EDT 2017
TβRII Regulates the Proliferation of Metanephric Mesenchyme Cells through Six2 In Vitro.
International journal of molecular sciences
Mao Z,Lyu Z,Huang L,Zhou Q,Weng Y
Tue Apr 18 00:00:00 EDT 2017
TβRII Regulates the Proliferation of Metanephric Mesenchyme Cells through Six2 In Vitro.
International journal of molecular sciences
Mao Z,Lyu Z,Huang L,Zhou Q,Weng Y
Tue Apr 18 00:00:00 EDT 2017
Postembryonic Nephrogenesis and Persistence of Six2-Expressing Nephron Progenitor Cells in the Reptilian Kidney.
PloS one
Camarata T,Howard A,Elsey RM,Raza S,O'Connor A,Beatty B,Conrad J,Solounias N,Chow P,Mukta S,Vasilyev A
Thu Apr 06 00:00:00 EDT 2017
Tridimensional Visualization and Analysis of Early Human Development.
Cell
Belle M,Godefroy D,Couly G,Malone SA,Collier F,Giacobini P,Chédotal A
Thu Mar 23 00:00:00 EDT 2017
Self-organisation after embryonic kidney dissociation is driven via selective adhesion of ureteric epithelial cells.
Development (Cambridge, England)
Lefevre JG,Chiu HS,Combes AN,Vanslambrouck JM,Ju A,Hamilton NA,Little MH
Wed Mar 15 00:00:00 EDT 2017
Novel fixed z-direction (FiZD) kidney primordia and an organoid culture system for time-lapse confocal imaging.
Development (Cambridge, England)
Saarela U,Akram SU,Desgrange A,Rak-Raszewska A,Shan J,Cereghini S,Ronkainen VP,Heikkilä J,Skovorodkin I,Vainio SJ
Wed Mar 15 00:00:00 EDT 2017
Lats1/2 Regulate Yap/Taz to Control Nephron Progenitor Epithelialization and Inhibit Myofibroblast Formation.
Journal of the American Society of Nephrology : JASN
McNeill H,Reginensi A
Wed Mar 01 00:00:00 EST 2017
In Vitro Propagation and Branching Morphogenesis from Single Ureteric Bud Cells.
Stem cell reports
Yuri S,Nishikawa M,Yanagawa N,Jo OD,Yanagawa N
Tue Feb 14 00:00:00 EST 2017
Repair after nephron ablation reveals limitations of neonatal neonephrogenesis.
JCI insight
Tögel F,Valerius MT,Freedman BS,Iatrino R,Grinstein M,Bonventre JV
Thu Jan 26 00:00:00 EST 2017
Temporally Distinct Six2-Positive Second Heart Field Progenitors Regulate Mammalian Heart Development and Disease.
Cell reports
Zhou Z,Wang J,Guo C,Chang W,Zhuang J,Zhu P,Li X
Tue Jan 24 00:00:00 EST 2017
Generation of nephron progenitor cells and kidney organoids from human pluripotent stem cells.
Nature protocols
Morizane R,Bonventre JV
Sun Jan 01 00:00:00 EST 2017
Notch signaling promotes nephrogenesis by downregulating Six2.
Development (Cambridge, England)
Chung E,Deacon P,Marable S,Shin J,Park JS
Tue Nov 01 00:00:00 EDT 2016
Cap mesenchyme cell swarming during kidney development is influenced by attraction, repulsion, and adhesion to the ureteric tip.
Developmental biology
Combes AN,Lefevre JG,Wilson S,Hamilton NA,Little MH
Sat Oct 15 00:00:00 EDT 2016
Six2 Is a Coordinator of LiCl-Induced Cell Proliferation and Apoptosis.
International journal of molecular sciences
Liu J,Ju P,Zhou Y,Zhao Y,Xie Y,Long Y,Gu Y,Ni D,Lyv Z,Mao Z,Hao J,Li Y,Wan Q,Kanyomse Q,Liu Y,Xiang Y,Wang R,Chen X,Zhang J,Liu X,Zhao H,Zhou Q,Li G
Thu Sep 08 00:00:00 EDT 2016
Zeb1 Is a Potential Regulator of Six2 in the Proliferation, Apoptosis and Migration of Metanephric Mesenchyme Cells.
International journal of molecular sciences
Gu Y,Zhao Y,Zhou Y,Xie Y,Ju P,Long Y,Liu J,Ni D,Cao F,Lyu Z,Mao Z,Hao J,Li Y,Wan Q,Kanyomse Q,Liu Y,Ren D,Ning Y,Li X,Zhou Q,Li B
Sat Aug 06 00:00:00 EDT 2016
A critical role for NF2 and the Hippo pathway in branching morphogenesis.
Nature communications
Reginensi A,Enderle L,Gregorieff A,Johnson RL,Wrana JL,McNeill H
Tue Aug 02 00:00:00 EDT 2016
Natural Scaffolds for Renal Differentiation of Human Embryonic Stem Cells for Kidney Tissue Engineering.
PloS one
Batchelder CA,Martinez ML,Tarantal AF
Mon Jun 20 00:00:00 EDT 2016
Preserved Nephrogenesis Following Partial Nephrectomy in Early Neonates.
Scientific reports
Kirita Y,Kami D,Ishida R,Adachi T,Tamagaki K,Matoba S,Kusaba T,Gojo S
Tue May 31 00:00:00 EDT 2016
Age-Dependent Pancreatic Gene Regulation Reveals Mechanisms Governing Human β Cell Function.
Cell metabolism
Arda HE,Li L,Tsai J,Torre EA,Rosli Y,Peiris H,Spitale RC,Dai C,Gu X,Qu K,Wang P,Wang J,Grompe M,Scharfmann R,Snyder MS,Bottino R,Powers AC,Chang HY,Kim SK
Tue May 10 00:00:00 EDT 2016
Selective In Vitro Propagation of Nephron Progenitors Derived from Embryos and Pluripotent Stem Cells.
Cell reports
Tanigawa S,Taguchi A,Sharma N,Perantoni AO,Nishinakamura R
Tue Apr 26 00:00:00 EDT 2016
Maintenance of Mouse Nephron Progenitor Cells in Aggregates with Gamma-Secretase Inhibitor.
PloS one
Yuri S,Nishikawa M,Yanagawa N,Jo OD,Yanagawa N
Fri Mar 04 00:00:00 EST 2016
Stromally expressed β-catenin modulates Wnt9b signaling in the ureteric epithelium.
PloS one
Boivin FJ,Sarin S,Lim J,Javidan A,Svajger B,Khalili H,Bridgewater D
Thu Feb 25 00:00:00 EST 2016
Nephron Progenitor But Not Stromal Progenitor Cells Give Rise to Wilms Tumors in Mouse Models with β-Catenin Activation or Wt1 Ablation and Igf2 Upregulation.
Neoplasia (New York, N.Y.)
Huang L,Mokkapati S,Hu Q,Ruteshouser EC,Hicks MJ,Huff V
Mon Feb 01 00:00:00 EST 2016
Urogenital development in Pallister-Hall syndrome is disrupted in a cell-lineage-specific manner by constitutive expression of GLI3 repressor.
Human molecular genetics
Blake J,Hu D,Cain JE,Rosenblum ND
Mon Feb 01 00:00:00 EST 2016
Prorenin receptor is critical for nephron progenitors.
Developmental biology
Song R,Preston G,Kidd L,Bushnell D,Sims-Lucas S,Bates CM,Yosypiv IV
Fri Jan 15 00:00:00 EST 2016
Concurrent BMP7 and FGF9 signalling governs AP-1 function to promote self-renewal of nephron progenitor cells.
Nature communications
Muthukrishnan SD,Yang X,Friesel R,Oxburgh L
Fri Dec 04 00:00:00 EST 2015
Cdc42 regulates epithelial cell polarity and cytoskeletal function during kidney tubule development.
Journal of cell science
Elias BC,Das A,Parekh DV,Mernaugh G,Adams R,Yang Z,Brakebusch C,Pozzi A,Marciano DK,Carroll TJ,Zent R
Tue Dec 01 00:00:00 EST 2015
Sall1 in renal stromal progenitors non-cell autonomously restricts the excessive expansion of nephron progenitors.
Scientific reports
Ohmori T,Tanigawa S,Kaku Y,Fujimura S,Nishinakamura R
Thu Oct 29 00:00:00 EDT 2015
Kidney organoids from human iPS cells contain multiple lineages and model human nephrogenesis.
Nature
Takasato M,Er PX,Chiu HS,Maier B,Baillie GJ,Ferguson C,Parton RG,Wolvetang EJ,Roost MS,Chuva de Sousa Lopes SM,Little MH
Thu Oct 22 00:00:00 EDT 2015
Intrinsic Age-Dependent Changes and Cell-Cell Contacts Regulate Nephron Progenitor Lifespan.
Developmental cell
Chen S,Brunskill EW,Potter SS,Dexheimer PJ,Salomonis N,Aronow BJ,Hong CI,Zhang T,Kopan R
Mon Oct 12 00:00:00 EDT 2015
A Cre-inducible fluorescent reporter for observing apical membrane dynamics.
Genesis (New York, N.Y. : 2000)
Pan X,Schnell U,Karner CM,Small EV,Carroll TJ
Tue Oct 06 00:00:00 EDT 2015
Renal stromal miRNAs are required for normal nephrogenesis and glomerular mesangial survival.
Physiological reports
Phua YL,Chu JY,Marrone AK,Bodnar AJ,Sims-Lucas S,Ho J
Thu Oct 01 00:00:00 EDT 2015
A developmentally plastic adult mouse kidney cell line spontaneously generates multiple adult kidney structures.
Biochemical and biophysical research communications
Webb CF,Ratliff ML,Powell R,Wirsig-Wiechmann CR,Lakiza O,Obara T
Fri Aug 07 00:00:00 EDT 2015
Fat4/Dchs1 signaling between stromal and cap mesenchyme cells influences nephrogenesis and ureteric bud branching.
Development (Cambridge, England)
Mao Y,Francis-West P,Irvine KD
Sat Aug 01 00:00:00 EDT 2015
Stromal Fat4 acts non-autonomously with Dchs1/2 to restrict the nephron progenitor pool.
Development (Cambridge, England)
Bagherie-Lachidan M,Reginensi A,Pan Q,Zaveri HP,Scott DA,Blencowe BJ,Helmbacher F,McNeill H
Sat Aug 01 00:00:00 EDT 2015
A synthetic niche for nephron progenitor cells.
Developmental cell
Brown AC,Muthukrishnan SD,Oxburgh L
Mon Jul 27 00:00:00 EDT 2015
Key pathways regulated by HoxA9,10,11/HoxD9,10,11 during limb development.
BMC developmental biology
Raines AM,Magella B,Adam M,Potter SS
Sun Jul 19 00:00:00 EDT 2015
Nonmuscle Myosin II Regulates the Morphogenesis of Metanephric Mesenchyme-Derived Immature Nephrons.
Journal of the American Society of Nephrology : JASN
Recuenco MC,Ohmori T,Tanigawa S,Taguchi A,Fujimura S,Conti MA,Wei Q,Kiyonari H,Abe T,Adelstein RS,Nishinakamura R
Fri May 01 00:00:00 EDT 2015
Fibroblast growth factor receptor-Frs2α signaling is critical for nephron progenitors.
Developmental biology
Di Giovanni V,Walker KA,Bushnell D,Schaefer C,Sims-Lucas S,Puri P,Bates CM
Wed Apr 01 00:00:00 EDT 2015
WT1 targets Gas1 to maintain nephron progenitor cells by modulating FGF signals.
Development (Cambridge, England)
Kann M,Bae E,Lenz MO,Li L,Trannguyen B,Schumacher VA,Taglienti ME,Bordeianou L,Hartwig S,Rinschen MM,Schermer B,Benzing T,Fan CM,Kreidberg JA
Wed Apr 01 00:00:00 EDT 2015
WT1 targets Gas1 to maintain nephron progenitor cells by modulating FGF signals.
Development (Cambridge, England)
Kann M,Bae E,Lenz MO,Li L,Trannguyen B,Schumacher VA,Taglienti ME,Bordeianou L,Hartwig S,Rinschen MM,Schermer B,Benzing T,Fan CM,Kreidberg JA
Wed Apr 01 00:00:00 EDT 2015
Renal progenitors derived from human iPSCs engraft and restore function in a mouse model of acute kidney injury.
Scientific reports
Imberti B,Tomasoni S,Ciampi O,Pezzotta A,Derosas M,Xinaris C,Rizzo P,Papadimou E,Novelli R,Benigni A,Remuzzi G,Morigi M
Fri Mar 06 00:00:00 EST 2015
Sall1 maintains nephron progenitors and nascent nephrons by acting as both an activator and a repressor.
Journal of the American Society of Nephrology : JASN
Kanda S,Tanigawa S,Ohmori T,Taguchi A,Kudo K,Suzuki Y,Sato Y,Hino S,Sander M,Perantoni AO,Sugano S,Nakao M,Nishinakamura R
Sat Nov 01 00:00:00 EDT 2014
Sall1 maintains nephron progenitors and nascent nephrons by acting as both an activator and a repressor.
Journal of the American Society of Nephrology : JASN
Kanda S,Tanigawa S,Ohmori T,Taguchi A,Kudo K,Suzuki Y,Sato Y,Hino S,Sander M,Perantoni AO,Sugano S,Nakao M,Nishinakamura R
Sat Nov 01 00:00:00 EDT 2014
The generation of kidney organoids by differentiation of human pluripotent cells to ureteric bud progenitor-like cells.
Nature protocols
Xia Y,Sancho-Martinez I,Nivet E,Rodriguez Esteban C,Campistol JM,Izpisua Belmonte JC
Sat Nov 01 00:00:00 EDT 2014
miR181c promotes apoptosis and suppresses proliferation of metanephric mesenchyme cells by targeting Six2 in vitro.
Cell biochemistry and function
Lv X,Mao Z,Lyu Z,Zhang P,Zhan A,Wang J,Yang H,Li M,Wang H,Wan Q,Wei H,Wang M,Wang N,Li X,Liu Y,Zhao H,Zhou Q
Wed Oct 01 00:00:00 EDT 2014
miR181c promotes apoptosis and suppresses proliferation of metanephric mesenchyme cells by targeting Six2 in vitro.
Cell biochemistry and function
Lv X,Mao Z,Lyu Z,Zhang P,Zhan A,Wang J,Yang H,Li M,Wang H,Wan Q,Wei H,Wang M,Wang N,Li X,Liu Y,Zhao H,Zhou Q
Wed Oct 01 00:00:00 EDT 2014
Ablation of the renal stroma defines its critical role in nephron progenitor and vasculature patterning.
PloS one
Hum S,Rymer C,Schaefer C,Bushnell D,Sims-Lucas S
Mon Sep 29 00:00:00 EDT 2014
Single cell dissection of early kidney development: multilineage priming.
Development (Cambridge, England)
Brunskill EW,Park JS,Chung E,Chen F,Magella B,Potter SS
Fri Aug 01 00:00:00 EDT 2014
Renal blood flow and oxygenation drive nephron progenitor differentiation.
American journal of physiology. Renal physiology
Rymer C,Paredes J,Halt K,Schaefer C,Wiersch J,Zhang G,Potoka D,Vainio S,Gittes GK,Bates CM,Sims-Lucas S
Fri Aug 01 00:00:00 EDT 2014
Identification and characterization of retinoic acid-responsive genes in mouse kidney development.
Genes to cells : devoted to molecular & cellular mechanisms
Takayama M,Miyatake K,Nishida E
Fri Aug 01 00:00:00 EDT 2014
Rapid and efficient differentiation of human pluripotent stem cells into intermediate mesoderm that forms tubules expressing kidney proximal tubular markers.
Journal of the American Society of Nephrology : JASN
Lam AQ,Freedman BS,Morizane R,Lerou PH,Valerius MT,Bonventre JV
Sun Jun 01 00:00:00 EDT 2014
Down-regulated Six2 by knockdown of neurofibromin results in apoptosis of metanephric mesenchyme cells in vitro.
Molecular and cellular biochemistry
Zhou P,Chen T,Fang Y,Wang H,Li M,Ma P,He L,Li Q,Liu T,Yang X,Nie F,Wang X,Yuan Y,Zhou L,Peng R,Liu Z,Zhou Q
Thu May 01 00:00:00 EDT 2014
Down-regulated Six2 by knockdown of neurofibromin results in apoptosis of metanephric mesenchyme cells in vitro.
Molecular and cellular biochemistry
Zhou P,Chen T,Fang Y,Wang H,Li M,Ma P,He L,Li Q,Liu T,Yang X,Nie F,Wang X,Yuan Y,Zhou L,Peng R,Liu Z,Zhou Q
Thu May 01 00:00:00 EDT 2014
β-Catenin overexpression in the metanephric mesenchyme leads to renal dysplasia genesis via cell-autonomous and non-cell-autonomous mechanisms.
The American journal of pathology
Sarin S,Boivin F,Li A,Lim J,Svajger B,Rosenblum ND,Bridgewater D
Thu May 01 00:00:00 EDT 2014
Lin28 sustains early renal progenitors and induces Wilms tumor.
Genes & development
Urbach A,Yermalovich A,Zhang J,Spina CS,Zhu H,Perez-Atayde AR,Shukrun R,Charlton J,Sebire N,Mifsud W,Dekel B,Pritchard-Jones K,Daley GQ
Thu May 01 00:00:00 EDT 2014
Global quantification of tissue dynamics in the developing mouse kidney.
Developmental cell
Short KM,Combes AN,Lefevre J,Ju AL,Georgas KM,Lamberton T,Cairncross O,Rumballe BA,McMahon AP,Hamilton NA,Smyth IM,Little MH
Mon Apr 28 00:00:00 EDT 2014
The number of fetal nephron progenitor cells limits ureteric branching and adult nephron endowment.
Cell reports
Cebrian C,Asai N,D'Agati V,Costantini F
Thu Apr 10 00:00:00 EDT 2014
Dicer function is required in the metanephric mesenchyme for early kidney development.
American journal of physiology. Renal physiology
Chu JY,Sims-Lucas S,Bushnell DS,Bodnar AJ,Kreidberg JA,Ho J
Tue Apr 01 00:00:00 EDT 2014
Osr1 acts downstream of and interacts synergistically with Six2 to maintain nephron progenitor cells during kidney organogenesis.
Development (Cambridge, England)
Xu J,Liu H,Park JS,Lan Y,Jiang R
Tue Apr 01 00:00:00 EDT 2014
Development of embryonic stem cells in recombinant kidneys.
Organogenesis
Rak-Raszewska A,Wilm B,Edgar D,Kenny S,Woolf AS,Murray P
Tue Mar 18 00:00:00 EDT 2014
Mdm2 is required for maintenance of the nephrogenic niche.
Developmental biology
Hilliard SA,Yao X,El-Dahr SS
Sat Mar 01 00:00:00 EST 2014
Stage specific requirement of Gfrα1 in the ureteric epithelium during kidney development.
Mechanisms of development
Keefe Davis T,Hoshi M,Jain S
Mon Feb 24 00:00:00 EST 2014
In situ histone landscape of nephrogenesis.
Epigenetics
McLaughlin N,Wang F,Saifudeen Z,El-Dahr SS
Sat Feb 01 00:00:00 EST 2014
Aberrant activation, nuclear localization, and phosphorylation of Yes-associated protein-1 in the embryonic kidney and Wilms tumor.
Pediatric blood & cancer
Murphy AJ,Pierce J,de Caestecker C,Libes J,Neblett D,de Caestecker M,Perantoni AO,Tanigawa S,Anderson JR,Dome JS,Das A,Carroll TJ,Lovvorn HN
Sat Feb 01 00:00:00 EST 2014
Redefining the in vivo origin of metanephric nephron progenitors enables generation of complex kidney structures from pluripotent stem cells.
Cell stem cell
Taguchi A,Kaku Y,Ohmori T,Sharmin S,Ogawa M,Sasaki H,Nishinakamura R
Thu Jan 02 00:00:00 EST 2014
Directing human embryonic stem cell differentiation towards a renal lineage generates a self-organizing kidney.
Nature cell biology
Takasato M,Er PX,Becroft M,Vanslambrouck JM,Stanley EG,Elefanty AG,Little MH
Wed Jan 01 00:00:00 EST 2014
Directed differentiation of human pluripotent cells to ureteric bud kidney progenitor-like cells.
Nature cell biology
Xia Y,Nivet E,Sancho-Martinez I,Gallegos T,Suzuki K,Okamura D,Wu MZ,Dubova I,Esteban CR,Montserrat N,Campistol JM,Izpisua Belmonte JC
Sun Dec 01 00:00:00 EST 2013
MiR-181b targets Six2 and inhibits the proliferation of metanephric mesenchymal cells in vitro.
Biochemical and biophysical research communications
lyu Z,Mao Z,Wang H,Fang Y,Chen T,Wan Q,Wang M,Wang N,Xiao J,Wei H,Li X,Liu Y,Zhou Q
Fri Nov 01 00:00:00 EDT 2013
Stromal-epithelial crosstalk regulates kidney progenitor cell differentiation.
Nature cell biology
Das A,Tanigawa S,Karner CM,Xin M,Lum L,Chen C,Olson EN,Perantoni AO,Carroll TJ
Sun Sep 01 00:00:00 EDT 2013
Stromal-epithelial crosstalk regulates kidney progenitor cell differentiation.
Nature cell biology
Das A,Tanigawa S,Karner CM,Xin M,Lum L,Chen C,Olson EN,Perantoni AO,Carroll TJ
Sun Sep 01 00:00:00 EDT 2013
Scaffolding proteins DLG1 and CASK cooperate to maintain the nephron progenitor population during kidney development.
Journal of the American Society of Nephrology : JASN
Ahn SY,Kim Y,Kim ST,Swat W,Miner JH
Sat Jun 01 00:00:00 EDT 2013
Six homeoproteins directly activate Myod expression in the gene regulatory networks that control early myogenesis.
PLoS genetics
Relaix F,Demignon J,Laclef C,Pujol J,Santolini M,Niro C,Lagha M,Rocancourt D,Buckingham M,Maire P
Mon Apr 01 00:00:00 EDT 2013
Six homeoproteins directly activate Myod expression in the gene regulatory networks that control early myogenesis.
PLoS genetics
Relaix F,Demignon J,Laclef C,Pujol J,Santolini M,Niro C,Lagha M,Rocancourt D,Buckingham M,Maire P
Mon Apr 01 00:00:00 EDT 2013
Yap- and Cdc42-dependent nephrogenesis and morphogenesis during mouse kidney development.
PLoS genetics
Reginensi A,Scott RP,Gregorieff A,Bagherie-Lachidan M,Chung C,Lim DS,Pawson T,Wrana J,McNeill H
Fri Mar 01 00:00:00 EST 2013
Six2 and Wnt regulate self-renewal and commitment of nephron progenitors through shared gene regulatory networks.
Developmental cell
Park JS,Ma W,O'Brien LL,Chung E,Guo JJ,Cheng JG,Valerius MT,McMahon JA,Wong WH,McMahon AP
Tue Sep 11 00:00:00 EDT 2012
Six2 and Wnt regulate self-renewal and commitment of nephron progenitors through shared gene regulatory networks.
Developmental cell
Park JS,Ma W,O'Brien LL,Chung E,Guo JJ,Cheng JG,Valerius MT,McMahon JA,Wong WH,McMahon AP
Tue Sep 11 00:00:00 EDT 2012
COUP-TFII is essential for metanephric mesenchyme formation and kidney precursor cell survival.
Development (Cambridge, England)
Yu CT,Tang K,Suh JM,Jiang R,Tsai SY,Tsai MJ
Sun Jul 01 00:00:00 EDT 2012
FGF9 and FGF20 maintain the stemness of nephron progenitors in mice and man.
Developmental cell
Barak H,Huh SH,Chen S,Jeanpierre C,Martinovic J,Parisot M,Bole-Feysot C,Nitschké P,Salomon R,Antignac C,Ornitz DM,Kopan R
Tue Jun 12 00:00:00 EDT 2012
Ureteric morphogenesis requires Fgfr1 and Fgfr2/Frs2α signaling in the metanephric mesenchyme.
Journal of the American Society of Nephrology : JASN
Sims-Lucas S,Di Giovanni V,Schaefer C,Cusack B,Eswarakumar VP,Bates CM
Sun Apr 01 00:00:00 EDT 2012
Integration potential of mouse and human bone marrow-derived mesenchymal stem cells.
Differentiation; research in biological diversity
Kuzma-Kuzniarska M,Rak-Raszewska A,Kenny S,Edgar D,Wilm B,Fuente Mora C,Davies JA,Murray P
Thu Mar 01 00:00:00 EST 2012
Dysfunction of fibroblasts of extrarenal origin underlies renal fibrosis and renal anemia in mice.
The Journal of clinical investigation
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Sat Oct 01 00:00:00 EDT 2011
Alk3 controls nephron number and androgen production via lineage-specific effects in intermediate mesoderm.
Development (Cambridge, England)
Di Giovanni V,Alday A,Chi L,Mishina Y,Rosenblum ND
Fri Jul 01 00:00:00 EDT 2011
The WTX tumor suppressor regulates mesenchymal progenitor cell fate specification.
Developmental cell
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Tue May 17 00:00:00 EDT 2011
Tight regulation of p53 activity by Mdm2 is required for ureteric bud growth and branching.
Developmental biology
Hilliard S,Aboudehen K,Yao X,El-Dahr SS
Sun May 15 00:00:00 EDT 2011
Canonical Wnt9b signaling balances progenitor cell expansion and differentiation during kidney development.
Development (Cambridge, England)
Karner CM,Das A,Ma Z,Self M,Chen C,Lum L,Oliver G,Carroll TJ
Fri Apr 01 00:00:00 EDT 2011
Wilms tumor chromatin profiles highlight stem cell properties and a renal developmental network.
Cell stem cell
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Fri Jun 04 00:00:00 EDT 2010
Misexpression of Six2 is associated with heritable frontonasal dysplasia and renal hypoplasia in 3H1 Br mice.
Developmental dynamics : an official publication of the American Association of Anatomists
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Tue Jul 01 00:00:00 EDT 2008