Peptide sequence: VFRSPLDLYS SHFLLPNFAD SHHRSILLAS SGGGNGAGGG GGAGGGSGGG
Sequence homology: Cow: 93%; Dog: 86%; Human: 100%; Mouse: 86%; Rat: 86%
This gene encodes a member of the sine oculis homeobox transcription factor family. The encoded protein plays a role in eye development. Mutations in this gene have been associated with holoprosencephaly type 2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Homeobox protein SIX3; sine oculis homeobox 3-like protein; Sine oculis homeobox homolog 3; sine oculis homeobox-like protein 3; sine oculis-related homeobox 3 homolog
Gene Aliases: BOS_11581; E130112M24Rik; HPE2; SIX3; Six3a; Six3alpha; Six3b; Six3beta