FIGURE: 1 / 1
Immunogen sequence: DGSTFTSEST TVQQGKVFLS SLAPSAVVYT VPNTGQTIGS VKQEGLERSL VFSQLMPVNQ NAQVNANLSS ENISGSGLHP LASSLVNVSP TH
Highest antigen sequence identity to the following orthologs: Mouse - 82%, Rat - 85%.
SIX4 gene ontology annotations related to this gene include anatomical structure development; embryonic cranial skeleton morphogenesis; fungiform papilla morphogenesis; generation of neurons; inner ear morphogenesis; male gonad development; male sex determination; metanephric mesenchyme development; myoblast migration; myotome development; negative regulation of neuron apoptotic process; negative regulation of satellite cell differentiation; negative regulation of transcription, DNA-templated; olfactory placode formation; pharyngeal system development; positive regulation of branching involved in ureteric bud morphogenesis; positive regulation of ureteric bud formation; protein localization to nucleus; regulation of branch elongation involved in ureteric bud branching; regulation of epithelial cell proliferation; regulation of protein localization; regulation of synaptic growth at neuromuscular junction; sarcomere organization; skeletal muscle fiber differentiation; thymus development; trigeminal ganglion development.
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Protein Aliases: Homeobox protein SIX4; Sine oculis homeobox homolog 4
Gene Aliases: AREC3; SIX4
UniProt ID: (Human) Q9UIU6
Entrez Gene ID: (Human) 51804
Molecular Function: homeodomain transcription factor