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This gene encodes a protein with 5-phosphatase activity toward polyphosphate inositol. The protein localizes to the cytosol in regions lacking actin stress fibers. It is thought that this protein may negatively regulate the actin cytoskeleton. Alternatively spliced transcript variants encoding different isoforms have been identified.
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Protein Aliases: Inositol polyphosphate 5-phosphatase K; Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase; Phosphatidylinositol-4,5-bisphosphate 5-phosphatase; PI-5-phosphatase related; putative PI-5-phosphatase; skeletal muscle and kidney enriched inositol polyphosphate phosphatase; Skeletal muscle and kidney-enriched inositol phosphatase
Gene Aliases: C62; INPP5K; PPS; SKIP
UniProt ID: (Human) Q9BT40, (Mouse) Q8C5L6
Entrez Gene ID: (Human) 51763, (Mouse) 19062
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