Positive Control: mouse brain
Predicted Reactivity: Human (100%), Rhesus Monkey (97%)
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.
DNMT2 encodes a member of the solute carrier family 11 protein family. The product of this gene transports divalent metals and is involved in iron absorption. Mutations in this gene are associated with hypochromic microcytic anemia with iron overload. A related solute carrier family 11 protein gene is located on chromosome 2. Multiple transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: DCT1; Divalent cation transporter 1; Divalent metal transporter 1; DMT-1; member 2; microcytic anemia, viable anaemia; Natural resistance-associated macrophage protein 2; NRAMP 2; NRAMP2; SLC11A2; solute carrier family 11 (proton-coupled divalent metal ion transporter); solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2; solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2; Solute carrier family 11 member 2
Gene Aliases: AHMIO1; DCT1; DMT1; mk; NRAMP2; OK/SW-cl.20; SLC11A2; van