Peptide sequence: ALIVITLPIG RKGKCPSSLY MAWLETLSQD LRPPVILIRG NQENVLTFYC
Sequence homology: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 93%; Rabbit: 100%; Rat: 100%; Zebrafish: 86%
This gene encodes a renal thiazide-sensitive sodium-chloride cotransporter that is important for electrolyte homeostasis. This cotransporter mediates sodium and chloride reabsorption in the distal convoluted tubule.
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Protein Aliases: Na-Cl cotransporter; Na-Cl symporter; NaCl electroneutral thiazide-sensitive cotransporter; NCC; NCCT; sodium chloride cotransporter; solute carrier family 12 (sodium/chloride transporter), member 3; Solute carrier family 12 (sodium/chloride transporters) member 3; solute carrier family 12 (sodium/chloride transporters), member 3; Solute carrier family 12 member 3; solute carrier family 12, member 3; thiazide-sensitive Na-Cl cotransporter; thiazide-sensitive sodium chloride cotransporter; Thiazide-sensitive sodium-chloride cotransporter
Gene Aliases: AI035291; BOS_17211; NCC; NCCT; si:ch211-122c9.4; SLC12A3; TSC; wu:fj83c03