Search
Bioss
SLC19A1 Polyclonal Antibody
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
BS-20879R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from mouse SLC19A1.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
TBS, pH 7.4, with 1% BSA, 50% glycerol
Contains
0.03% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
Transport of folate compounds into mammalian cells can occur via receptor-mediated or carrier-mediated mechanisms. A functional coordination between these 2 mechanisms has been proposed to be the method of folate uptake in certain cell types. Methotrexate (MTX) is an antifolate chemotherapeutic agent that is actively transported by the carrier-mediated uptake system. RFC1 plays a role in maintaining intracellular concentrations of folate.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: folate transporter 1; IFC-1; intestinal folate carrier 1; intestinal folate carrier protein; methotrexate carrier 1; methotrexate carrier 2; methotrexate carrier 5; methotrexate carrier 6; organic anion transporter; plasma membrane folate antiporter SLC19A1; reduced folate carrier 1; RFC-1; RFC1; solute carrier family 19 (folate transporter), member 1; solute carrier family 19 (sodium/hydrogen exchanger), member 1; solute carrier family 19 member 1; unnamed protein product
Gene Aliases: MTX-1; MTX1; RFC; RFC-1; RFC1
UniProt ID: (Mouse) P41438, (Rat) Q62866
Entrez Gene ID: (Mouse) 20509, (Rat) 29723
folic acid binding
folic acid transporter activity
reduced folate carrier activity
antiporter activity
methotrexate transporter activity
transmembrane transporter activity
xenobiotic transporter activity
cyclic-GMP-AMP binding
vitamin transmembrane transporter activity
cyclic-GMP-AMP transmembrane transporter activity
drug transmembrane transport
female pregnancy
response to xenobiotic stimulus
response to toxic substance
folic acid transport
vitamin transport
methotrexate transport
transmembrane transport
anion transmembrane transport
reduced folate transmembrane transport
cyclic-GMP-AMP transmembrane import across plasma membrane
positive regulation of cGAS/STING signaling pathway
folic acid import into cell
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support