Immunogen sequence: NLVEATFKQY RTKTTPVVKS PKVAPEEAPP RRILIYGVQE ENGSHVQNFA LDLTPPPEVV YKSEPGTSDG M
Highest antigen sequence identity to the following orthologs: Mouse - 87%, Rat - 89%.
This gene belongs to the sodium:dicarboxylate (SDF) symporter (TC 2.A.23) family, SLC1A7 subfamily. As transportor of L-glutamate; the L-glutamate uptake is sodium- and voltage-dependent and chloride-independent. Its associated chloride conductance may participate in visual processing.It interacts with the PDZ domains of DLG4. Expressed primarily in retina. Detectable in liver, heart, muscle and brain.
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Protein Aliases: AAAT; EAAT5; Excitatory amino acid transporter 5; excitatory amino acid transporter 5 (retinal glutamate transporter); Retinal glutamate transporter; solute carrier family 1 (glutamate transporter), member 7; Solute carrier family 1 member 7
Gene Aliases: AAAT; EAAT5; SLC1A7
UniProt ID: (Human) O00341
Entrez Gene ID: (Human) 6512