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Product Details
PA5-80014
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide corresponding to a sequence at the C-terminus of human SLC22A1 (533-550aa RKAKPKENTIYLKVQTSE).
Conjugate
Unconjugated
Form
Lyophilized
Concentration
500 µg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS with 5mg BSA
Contains
0.05mg sodium azide, 0.05mg thimerosal
Storage conditions
-20°C
RRID
AB_2747129
Product Specific Information
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Target Information
Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. This gene is one of three similar cation transporter genes located in a cluster on chromosome 6. The encoded protein contains twelve putative transmembrane domains and is a plasma integral membrane protein. Two transcript variants encoding two different isoforms have been found for this gene, but only the longer variant encodes a functional transporter.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 1-Oct; DKFZp313N1010; FLJ25043; FLJ37489; H oct1_cds; hOCT1; Organic cation transporter 1; solute carrier family 22 (organic cation transporter), member 1; Solute carrier family 22 member 1; SYK
Gene Aliases: HOCT1; OCT1; oct1_cds; SLC22A1
UniProt ID: (Human) O15245
Entrez Gene ID: (Human) 6580
Molecular Function:
secondary carrier transporter
neurotransmitter transport
drug transmembrane transport
establishment or maintenance of transmembrane electrochemical gradient
organic cation transport
quaternary ammonium group transport
dopamine transport
norepinephrine transport
epinephrine transport
protein homooligomerization
ammonium transmembrane transport
acetate ester transport
acetylcholine transmembrane transporter activity
dopamine transmembrane transporter activity
norepinephrine transmembrane transporter activity
protein binding
secondary active organic cation transmembrane transporter activity
organic cation transmembrane transporter activity
quaternary ammonium group transmembrane transporter activity
protein homodimerization activity
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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