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SLC22A6/OAT1 Polyclonal Antibody
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FIGURE: 1 / 3
SLC22A6/OAT1 Antibody (600-401-R18) in IHC (P)
Immunohistochemistry analysis of Anti-SLC22A6 using anti-SLC22A6 antibody. SLC22A6 was detected in paraffin-embedded section of human mammary cancer tissues. Heat mediated antigen retrieval was performed in citrate buffer (pH 6, epitope retrieval solution) for 20 mins. The tissue section was blocked with 10% goat serum. The tissue section was then incubated with 1μg/mL rabbit anti-SLC22A6 antibody overnight... View More
Product Details
600-401-R18
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
SLC22A6/OAT1 affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to a sequence at the C-terminal of human SLC22A6/OAT1.
Conjugate
Form
Lyophilized
Concentration
0.5 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS with 5mg BSA
Contains
0.05mg sodium azide, 0.05mg thimerosal
Storage conditions
4°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
The protein is involved in the sodium-dependent transport and excretion of organic anions, some of which are potentially toxic. The encoded protein is an integral membrane protein and may be localized to the basolateral membrane.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: hOAT1; hPAHT; hROAT1; OAT1; Organic anion transporter 1; organic cationic transporter-like 1; PAH transporter; para-aminohippurate transporter; Renal organic anion transporter 1; rOAT1; rROAT1; solute carrier family 22 (organic anion transporter), member 6; Solute carrier family 22 member 6; solute carrier family 22, member 6; unnamed protein product
Gene Aliases: HOAT1; OAT1; Orctl1; PAHT; ROAT1; SLC22A6
UniProt ID: (Human) Q4U2R8, (Rat) O35956
Entrez Gene ID: (Human) 9356, (Rat) 29509
inorganic anion exchanger activity
protein binding
organic anion transmembrane transporter activity
prostaglandin transmembrane transporter activity
alpha-ketoglutarate transmembrane transporter activity
antiporter activity
sodium-independent organic anion transmembrane transporter activity
transmembrane transporter activity
chloride ion binding
identical protein binding
xenobiotic transporter activity
anion:anion antiporter activity
protein homodimerization activity
secondary carrier transporter
anion transport
inorganic anion transport
organic anion transport
prostaglandin transport
alpha-ketoglutarate transport
xenobiotic transport
sodium-independent organic anion transport
transmembrane transport
metanephric proximal tubule development
renal tubular secretion
response to methotrexate
ion transmembrane transport
protein homooligomerization
anion transmembrane transport
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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