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Antibody detects endogenous levels of total SLC25A21.
SLC25A21 is a homolog of the S. cerevisiae ODC proteins, mitochondrial carriers that transport C5-C7 oxodicarboxylates across inner mitochondrial membranes. One of the species transported by ODC is 2-oxoadipate, a common intermediate in the catabolism of lysine, tryptophan, and hydroxylysine in mammals. Within mitochondria, 2-oxoadipate is converted into acetyl-CoA.
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Protein Aliases: MGC126570; Mitochondrial 2-oxoadipate carrier; Mitochondrial 2-oxodicarboxylate carrier; mitochondrial solute carrier family 25 member 21; ODC; oxodicarboxylate carrier; solute carrier family 25 (mitochondrial oxoadipate carrier), member 21; solute carrier family 25 (mitochondrial oxodicarboxylate carrier), member 21; Solute carrier family 25 member 21
Gene Aliases: 9930033G19Rik; A630030I10; BB158148; ODC; ODC1; SLC25A21
UniProt ID: (Human) Q9BQT8, (Rat) Q99JD3, (Mouse) Q8BZ09
Entrez Gene ID: (Human) 89874, (Rat) 171151, (Mouse) 217593
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