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Proteintech
SLC25A33 Polyclonal Antibody
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Product Details
17794-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
SLC25A33 Fusion Protein Ag11926 (1-321 aa encoded by BC073135)
Conjugate
Form
Liquid
Concentration
0.14 mg/mL
Amount
21 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MATGGQQKE NTLLHLFAGG CGGTVGAIFT CPLEVIKTRL QSSRLALRTV YYPQVHLGTI SGAGMVRPTS VTPGLFQVLK SILEKEGPKS LFRGLGPNLV GVAPSRAVYF ACYSKAKEQF NGIFVPNSNI VHIFSAGSAA FITNSLMNPI WMVKTRMQLE QKVRGSKQMN TLQCARYVYQ TEGIRGFYRG LTASYAGISE TIICFAIYES LKKYLKEAPL ASSANGTEKN STSFFGLMAA AALSKGCASC IAYPHEVIRT RLREEGTKYK SFVQTARLVF REEGYLAFYR GLFAQLIRQI PNTAIVLSTY ELIVYLLEDR TQ (1-321 aa encoded by BC073135)
Target Information
The SLC25A33 gene belongs to the solute carrier family 25 (SLC25), which is the largest family of mitochondrial transport proteins comprising 53 members. The SLC25A33 gene encodes a mitochondrial transporter responsible for the transport of pyrimidine nucleotides, specifically deoxyadenine nucleotides, across the inner mitochondrial membrane. This transport is crucial for nucleotide salvage pathways, ensuring the synthesis and maintenance of mitochondrial DNA. SLC25A33 also plays a significant role in cellular energy metabolism, linking cytosolic and mitochondrial nucleotide pools. Mutations or dysregulation of this gene can impact mitochondrial function and have been implicated in various metabolic disorders and mitochondrial diseases.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: BMSC-MCP; Bone marrow stromal cell mitochondrial carrier protein; huBMSC-MCP; MCP; mitochondrial carrier protein; novel mitochondrial carrier protein; Protein PNC1; solute carrier family 25 (pyrimidine nucleotide carrier), member 33; Solute carrier family 25 member 33
Gene Aliases: BMSC-MCP; PNC1; SLC25A33
UniProt ID: (Human) Q9BSK2
Entrez Gene ID: (Human) 84275
mitochondrial genome maintenance
regulation of oxidative phosphorylation
transcription from mitochondrial promoter
nucleotide transport
pyrimidine nucleotide transport
mitochondrion organization
positive regulation of cell proliferation
positive regulation of cell growth
mitochondria-nucleus signaling pathway
cellular response to insulin stimulus
mitochondrial respiratory chain complex III assembly
regulation of mitochondrial membrane potential
regulation of reactive oxygen species biosynthetic process
cellular response to insulin-like growth factor stimulus
mitochondrial pyrimidine nucleotide import
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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