PA5-29967 targets SLC25A6 in IF and WB applications and shows reactivity with Human samples.
The PA5-29967 immunogen is recombinant fragment corresponding to a region within amino acids 57 and 298 of Human SLC25A6.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.
This gene is a member of the mitochondrial carrier subfamily of solute carrier protein genes. The product of this gene functions as a gated pore that translocates ADP from the mitochondrial matrix into the cytoplasm. The protein is implicated in the function of the permability transition pore complex (PTPC), which regulates the release of mitochondrial products that induce apoptosis. The human genome contains several non-transcribed pseudogenes of this gene.
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Protein Aliases: AAC3; Adenine nucleotide translocator 3; ADP,ATP carrier protein 3; ADP,ATP carrier protein, isoform T2; ADP,ATP carrier protein, liver; ADP/ATP translocase 3; ADP/ATP translocase 3, N-terminally processed; ADP/ATP translocator of liver; ANT 2; ANT 3; ANT3; ANT3Y; ATP carrier protein; ATP carrier protein 3; liver; solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6; Solute carrier family 25 member 6
Gene Aliases: AAC3; ANT; ANT 2; ANT 3; ANT3; ANT3Y; CDABP0051; SLC25A6
UniProt ID: (Human) P12236
Entrez Gene ID: (Human) 293
Molecular Function: RNA binding protein amino acid transporter calcium-binding protein calmodulin intracellular calcium-sensing protein mitochondrial carrier protein nucleic acid binding ribosomal protein transfer/carrier protein transporter