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This target displays homology in the following species: Cow: 100%; Dog: 100%; Goat: 86%; Guinea Pig: 93%; Horse: 93%; Human: 100%; Mouse: 93%; Pig: 100%; Rabbit: 93%; Rat: 100%; Sheep: 100%; Zebrafish: 93%
This gene is a member of the mitochondrial carrier subfamily of solute carrier protein genes. The product of this gene functions as a gated pore that translocates ADP from the mitochondrial matrix into the cytoplasm. The protein is implicated in the function of the permability transition pore complex (PTPC), which regulates the release of mitochondrial products that induce apoptosis. The human genome contains several non-transcribed pseudogenes of this gene.
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Protein Aliases: Adenine nucleotide translocator 3; ADP,ATP carrier protein 3; ADP,ATP carrier protein, isoform T2; ADP,ATP carrier protein, liver; ADP/ATP translocase 3; ADP/ATP translocase 3, N-terminally processed; ADP/ATP translocator of liver; ANT 2; ANT 3; solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6; Solute carrier family 25 member 6
Gene Aliases: AAC3; ANT; ANT 2; ANT 3; ANT3; ANT3Y; CDABP0051; SLC25A6
UniProt ID: (Human) P12236
Entrez Gene ID: (Human) 293
Molecular Function: transfer/carrier protein