SLC27A1 is a protein coding gene. Mediates the ATP-dependent import of long-chain fatty acids (LCFA) into the cell by mediating their translocation at the plasma membrane. Has also an acyl-CoA ligase activity for long-chain and very-long-chain fatty acids. May act directly as a bona fide transporter, or alternatively, in a cytoplasmic or membrane-associated multimeric protein complex to trap and draw fatty acids towards accumulation. Plays a pivotal role in regulating available LCFA substrates from exogenous sources in tissues undergoing high levels of beta-oxidation or triglyceride synthesis. May be involved in regulation of cholesterol metabolism.
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Protein Aliases: ACSVL5FATP-1; EC 6.2.1; FATP-1; Fatty acid transport protein; fatty acid transport protein 1; FLJ00336; Long-chain fatty acid transport protein 1; MGC71751; solute carrier family 27 (fatty acid transporter), member 1; Solute carrier family 27 member 1; solute carrier family 27, member 1
Gene Aliases: ACSVL5; FATP; FATP-1; FATP1; SLC27A1