Search
Invitrogen
SLC30A1 Polyclonal Antibody
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Additional Information:
{{banner.description}}
Product Details
PA5-37463
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide corresponding to amino acids 200-250 of human ZnT-1
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
This antibody detects endogenous protein at a molecular weight of 55 kDa.
Purity is >95% by SDS-PAGE.
Target Information
Zinc, an essential element required for cell proliferation and differentiation, plays a role in a diverse array of cellular functions, including acting as a cofactor for numerous enzymes and transcription factors and as a neuroregulator. The zinc transporter (ZnT) family regulates the supply of zinc within cells, and its members are characterized by containing six membrane-spanning domains, a large histidine-rich intracellular loop, and a C-terminal tail. ZnT-1, a ubiquitous protein of approximately 60 kDa, localizes to the plasma membrane to aid in the export of zinc out of cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Proton-coupled zinc antiporter SLC30A1; solute carrier family 30 (zinc transporter), member 1; Solute carrier family 30 member 1; solute carrier family 30, member 1; zinc resistance conferring homolog; Zinc transporter 1; ZnT-1
Gene Aliases: AI839647; C130040I11Rik; SLC30A1; ZNT1; ZRC1
UniProt ID: (Human) Q9Y6M5, (Rat) Q62720, (Mouse) Q60738
Entrez Gene ID: (Human) 7779, (Rat) 58976, (Mouse) 22782
in utero embryonic development
zinc II ion transport
cellular calcium ion homeostasis
cellular zinc ion homeostasis
negative regulation of neurotransmitter secretion
calcium ion import
cadmium ion transmembrane transport
zinc II ion transmembrane transport
negative regulation of zinc ion transmembrane import
detoxification of cadmium ion
negative regulation of calcium ion import
transport
ion transport
cation transport
transmembrane transport
detoxification of zinc ion
defense response to bacterium
positive regulation of dendritic spine morphogenesis
zinc ion import into organelle
zinc export across plasma membrane
regulation of postsynaptic density protein 95 clustering
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support