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SLC37A4 Antibody (PA5-89908) in IHC (P)
Immunohistochemistry analysis of SLC37A4 in paraffin-embedded mouse brain. Samples were incubated with SLC37A4 Polyclonal antibody (Product # PA5-89908) using a dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.
Product Details
PA5-89908
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 300 to the C-terminus of human SLC37A4
Conjugate
Unconjugated
Form
Liquid
Concentration
2.58 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.01% thimerosal
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
RRID
AB_2805835
Product Specific Information
Immunogen sequence: RHGLLLFMMA GMTVSMYLFR VTVTSDSPKL WILVLGAVFG FSSYGPIALF GVIANESAPP NLCGTSHAIV GLMANVGGFL AGLPFSTIAK HYSWSTAFWV AEVICAASTA AFFLLRNIRT KMGRVSKKAE; Positive Samples: Mouse kidney, Rat liver; Cellular Location: Endoplasmic reticulum membrane, Multi-pass membrane protein
Target Information
SLC37A4 transports glucose-6-phosphate from the cytoplasm to the lumen of the endoplasmic reticulum. It forms with glucose-6-phosphatase the complex responsible for glucose production through glycogenolysis and gluconeogenesis. Hence, it plays a central role in homeostatic regulation of blood glucose levels.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: glucose 6-phosphate transporter; Glucose-5-phosphate transporter; glucose-6-phosphatase transport protein 1; glucose-6-phosphatase, transport (glucose) protein 3; glucose-6-phosphatase, transport (glucose-6-phosphate) protein 1; glucose-6-phosphatase, transport (phosphate/pyrophosphate) protein 2; glucose-6-phosphatase, transport protein 1; Glucose-6-phosphate exchanger SLC37A4; Glucose-6-phosphate translocase; MGC15729; microsomal glucose-6-phosphate transporter; solute carrier family 37 (glucose-6-phosphate transporter), member 4; solute carrier family 37 (glycerol-6-phosphate transporter), member 4; Solute carrier family 37 member 4; Transformation-related gene 19 protein; transporter; TRG-19
Gene Aliases: G6PT; G6PT1; G6PT2; G6PT3; GSD-1b; GSD1b; GSD1c; GSD1d; mG6PT; PRO0685; SLC37A4; TRG-19; TRG19
UniProt ID: (Human) O43826
Entrez Gene ID: (Human) 2542, (Mouse) 14385, (Rat) 29573
Molecular Function:
primary active transporter
positive regulation of defense response to virus by host
glucose metabolic process
transport
glucose transport
glucose-6-phosphate transport
phosphate ion transmembrane transport
mitophagy in response to mitochondrial depolarization
xenophagy
neutrophil homeostasis
cytokine production
myeloid progenitor cell differentiation
glycogen metabolic process
lactate metabolic process
triglyceride metabolic process
anion transport
cellular calcium ion homeostasis
steroid metabolic process
response to glucose
response to organic cyclic compound
neutrophil chemotaxis
negative regulation of chemokine production
post-embryonic hemopoiesis
glucose homeostasis
cholesterol homeostasis
positive regulation of catalytic activity
respiratory burst
phosphate ion homeostasis
transmembrane transport
response to nutrient
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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