Under hypertonic conditions the induction of SLC38A2/SNAT2 leads to the stimulation of transport system A and to the increase in the cell content of amino acids. Its amino acid response element, along with a nearby conserved CAAT box, has enhancer activity in that it functions in an orientation and position independent manner, and it confers regulated transcription to a heterologous promoter.
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Protein Aliases: amino acid transporter 2; Amino acid transporter A2; Protein 40-9-1; Sodium-coupled neutral amino acid transporter 2; Solute carrier family 38 member 2; solute carrier family 38, member 2; System A amino acid transporter 2; System A transporter 1; System N amino acid transporter 2
Gene Aliases: ATA2; KIAA1382; PRO1068; SAT2; SLC38A2; SNAT2
UniProt ID: (Human) Q96QD8
Entrez Gene ID: (Human) 54407
Molecular Function: amino acid transporter