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Invitrogen
SLC38A3 Polyclonal Antibody
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Product Details
PA5-65113
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Human SLC38A3. Recombinant protein control fragment (Product #RP-105871).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Amount
10 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: KFHVPCPLPPN FNNTTGNFSH VEIVKEKVQL QVEPEASAFC TPSYFTLNSQ T
Highest antigen sequence identity to the following orthologs - mouse 69%, rat 72%.
Target Information
As a sodium-dependent amino acid/proton antiporter, SLC38A3 mediates electrogenic cotransport of glutamine and sodium ions in exchange for protons. It also recognizes histidine, asparagine and alanine. It may mediate amino acid transport in either direction under physiological conditions and play a role in nitrogen metabolism and synaptic transmission.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: hSN1; N-system amino acid transporter 1; Na(+)-coupled neutral amino acid transporter 3; SLC38A3; Sodium-coupled neutral amino acid transporter 3; Solute carrier family 38 member 3; System N amino acid transporter 1; system N1 Na+ and H+-coupled glutamine transporter; unnamed protein product
Gene Aliases: DEE102; G17; NAT1; SLC38A3; SN1; SNAT3
UniProt ID: (Human) Q99624
Entrez Gene ID: (Human) 10991
L-histidine transmembrane transporter activity
neutral amino acid:sodium symporter activity
amino acid transmembrane transporter activity
L-alanine transmembrane transporter activity
L-asparagine transmembrane transporter activity
L-glutamine transmembrane transporter activity
symporter activity
antiporter activity
L-glutamine, sodium:proton antiporter activity
L-asparagine, sodium:proton antiporter activity
L-histidine, sodium:proton antiporter activity
amino acid transmembrane transport
ion transport
sodium ion transport
amino acid transport
asparagine transport
glutamine transport
female pregnancy
glutamine secretion
L-alanine transport
histidine transport
positive regulation of transcription from RNA polymerase II promoter
cellular response to potassium ion starvation
amino acid homeostasis
transport across blood-brain barrier
L-histidine transport
L-glutamine import across plasma membrane
L-histidine import across plasma membrane
L-asparagine import across plasma membrane
positive regulation of glutamine transport
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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