Invitrogen

SLC39A6 Polyclonal Antibody

Product Image Gallery

SLC39A6 Antibody in Western Blot (WB) — Western blot analysis of SLC39A6 in 293 cell lysate (left lane: treated with blocking peptide). Samples were incubated with SLC39A6 polyclonal antibody (Product # PA5-100155).

SLC39A6 Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemistry analysis of paraffin-embedded SLC39A6 in human pancreas cancer tissue. Antigen retrieval was performed using citrate buffer. Samples were blocked with blocking buffer (1.5 hr, 22°C), incubated with SLC39A6 polyclonal antibody (Product # PA5-100155) using a dilution of 1:100 (1.5 hr, 22°C), followed by HRP conjugated goat anti-rabbit.

SLC39A6 Antibody in Immunofluorescence (IF) — Immunofluorescent analysis of SLC39A6 in HeLa cells. Samples were fixed with paraformaldehyde, permeabilized with 0.1% Triton X-100, blocked with 10% serum (45 min at 25°C), incubated with mouse anti-beta tubulin and SLC39A6 polyclonal antibody (Product # PA5-100155) using a dilution of 1:200 (1 hr, 37°C), and followed by goat anti-rabbit IgG Alexa Fluor 594 (red) and goat anti-mouse IgG Alexa Fluor 488 (green).

Product Details

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2000

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

Immunocytochemistry (ICC)

1:100-1:500

Immunofluorescence (IF)

1:100-1:500

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A synthesized peptide derived from human LIV-1/ZIP6, corresponding to a region within the internal amino acids.

Conjugate

Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4, with 50% glycerol, 150mM NaCl

Contains

0.02% sodium azide

Storage conditions

-20°C

RRID

AB_2815685

Target Information

This gene encodes a protein which interacts with the carboxy-terminus of transcription initiation factor TFIIF, a transcription factor which regulates elongation as well as initiation by RNA polymerase II. The protein may also represent a component of an RNA polymerase II holoenzyme complex. Alternative splicing of this gene results in two transcript variants encoding 2 different isoforms.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: endoplasmic reticulum membrane protein; Endoplasmic reticulum membrane-linked protein; Ermelin; Estrogen-regulated protein LIV-1; LIV-1 protein, estrogen regulated; slc39a6 {ECO:0000312|EMBL:AAH97493.1}; solute carrier family 39 (metal ion transporter), member 6; solute carrier family 39 (zinc transporter), member 6; Solute carrier family 39 member 6; Zinc transporter ZIP6; ZIP-6; Zrt- and Irt-like protein 6

Gene Aliases: Ermelin; LIV-1; LIV1; SLC39A6; ZIP6

UniProt ID: (Human) Q13433, (Mouse) Q8C145, (Rat) Q4V887

Entrez Gene ID: (Human) 25800, (Mouse) 106957, (Rat) 291733

Molecular Function: transporter