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SLC46A1 Polyclonal Antibody
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Product Details
OSS00366W-100UL
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ Ig
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide from aa region 350-450 of human SLC46A1 conjugated to an immunogenic carrier protein was used as the antigen
Conjugate
Form
Lyophilized
Concentration
Conc. Not Determined
Storage buffer
whole serum
Contains
no preservative
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability.
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
Specificity of this antibody: SLC46A1.
Target Information
Has been shown to act both as an intestinal proton-coupled high-affinity folate transporter and as an intestinal heme transporter which mediates heme uptake from the gut lumen into duodenal epithelial cells. The iron is then released from heme and may be transported into the bloodstream. Dietary heme iron is an important nutritional source of iron. Shows a higher affinity for folate than heme.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Heme carrier protein 1; HsPCFT; PCFT/HCP1; Proton-coupled folate transporter; solute carrier family 46 (folate transporter), member 1; Solute carrier family 46 member 1; unnamed protein product
Gene Aliases: G21; HCP1; hPCFT; HsPCFT; PCFT; SLC46A1
UniProt ID: (Human) Q96NT5
Entrez Gene ID: (Human) 113235
cellular iron ion homeostasis
folic acid transport
heme transport
heme metabolic process
tetrahydrofolate biosynthetic process
folic acid metabolic process
methotrexate transport
transmembrane transport
intestinal folate absorption
reduced folate transmembrane transport
hydrogen ion transmembrane transport
folic acid import into cell
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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