The antibody detects endogenous levels of total SLC4A1 protein.
The Band 3 protein is the most abundant integral protein of human erythrocyte membranes and functions as the major anion transporter polypeptide of erythrocytes. Band 3 is a 90-100 kD protein, its microheterogeneity is ascribed mainly to the structural heterogeneity of the carbohydrate moiety. The C-terminal portion of the molecule spans the membrane several times, and is responsible for anion transport. The N-terminal portion, comprising almost half of the polypeptide chain of Band 3, is located inside the red cell and interacts with cytoskeletal and cytoplasmic proteins such as ankyrin.
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Protein Aliases: AE 1; AE1; Anion exchange protein 1; anion exchanger 1; anion exchanger-1; Band 3 anion transport protein; BND3; CD233; DI; Diego blood group; EMPB3; EPB3; erythrocyte membrane protein band 3; erythroid anion exchange protein; Froese blood group; MGC116750; MGC116753; MGC126619; MGC126623; RTA1A; solute carrier family 4 (anion exchanger), member 1 (Diego blood group); Solute carrier family 4 member 1; solute carrier family 4, anion exchanger, member 1 (erythrocyte membrane protein band 3, Diego blood group); solute carrier family 4, anion exchanger, number 1; SW; Swann blood group; Waldner blood group; WD; WD1; WR; Wright blood group
Gene Aliases: AE1; BND3; CD233; CHC; DI; EMPB3; EPB3; FR; RTA1A; SAO; SLC4A1; SPH4; SW; WD; WD1; WR
UniProt ID: (Human) P02730
Entrez Gene ID: (Human) 6521