SLC6A15 (solute carrier family 6 (neutral amino acid transporter), member 15), also known as sodium-dependent neutral amino acid transporter B(0)AT2, transporter v7-3, NTT73 or sodium-coupled branched-chain amino-acid transporter 1 (SBAT1), is a 730 amino acid multi-pass membrane protein that acts as a sodium-dependent neutral amino acid transporter. A member of the sodium neurotransmitter symporter (SNF) family and SLC6A15 subfamily, SLC6A15 differs from other members of its family in that it does not appear to be chloride-dependent. SLC6A15 is expressed in brain and is encoded by a gene that maps to human chromosome 12, which encodes over 1,100 genes and comprises approximately 4. 5% of the human genome. Chromosome 12 is associated with a variety of diseases and afflictions, including hypochondrogenesis, achondrogenesis, Kniest dysplasia, Noonan syndrome and trisomy 12p, which causes facial developmental defects and seizure disorders.
Protein Aliases: homolog of rat orphan transporter v7-3; orphan sodium- and chloride-dependent neurotransmitter transporter NTT73; orphan transporter v7-3; Sodium- and chloride-dependent neurotransmitter transporter NTT73; Sodium-coupled branched-chain amino-acid transporter 1; Sodium-dependent neutral amino acid transporter B(0)AT2; sodium/chloride dependent neurotransmitter transporter Homo sapiens orphan neurotransmitter transporter NTT7; solute carrier family 6 (neurotransmitter transporter), member 15; solute carrier family 6 (neutral amino acid transporter), member 15; Solute carrier family 6 member 15; solute carrier family 6, member 15; Transporter v7-3
Gene Aliases: B0AT2; hv7-3; NTT73; SBAT1; SLC6A15; V7-3
UniProt ID: (Human) Q9H2J7
Entrez Gene ID: (Human) 55117