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          • Primary Antibodies ›
          • Norepinephrine Transporter Antibodies

          Osenses

          SLC6A2 Polyclonal Antibody

          2 References
          View all (11) Norepinephrine Transporter antibodies

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          Cite SLC6A2 Polyclonal Antibody

          Additional Information:
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          SLC6A2 Polyclonal Antibody

          Product Details

          OSS00337W-100UL

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:300-1:2,000
          -

          Immunohistochemistry (IHC)

          1:300-1:2,000
          -

          Miscellaneous PubMed (Misc)

          -
          View 2 publications 2 publications
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Rabbit / Ig

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          A synthetic peptide from aa region 5-85 of human SLC6A2 conjugated to an immunogenic carrier protein was used as the antigen
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Lyophilized

          Concentration

          Conc. Not Determined

          Storage buffer

          whole serum

          Contains

          no preservative

          Storage conditions

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability.

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          Product Specific Information

          Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.

          Specificity of this antibody: SLC6A2.

          Target Information

          Norepinephrine Transporter [NET, or noradrenaline transporter (NAT)] is a monoamine transporter that transports the neurotransmitter noradrenaline from the synapse back to its vesicles for storage until later use. It also appears to transport the neurotransmitter dopamine in the same way, but to a lesser degree. Studies have shown a decrease in NET levels in the locus coeruleus in patients diagnosed with major depression. Cocaine, amphetamines and many therapeutic antidepressants, such as the SNRIs (serotonin-norepinephrine reuptake inhibitors) and the tricyclic antidepressants (TCAs) act to raise noradrenaline. Furthermore, deficits in the NET gene have been associated with ADHD.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          Bioinformatics

          Protein Aliases: NET; neurotransmitter transporter; noradrenaline; Norepinephrine transporter; Sodium-dependent noradrenaline transporter; solute carrier family 6 (neurotransmitter transporter), member 2; solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2; Solute carrier family 6 member 2; solute carrier family 6 member 5

          View more View less

          Gene Aliases: NAT1; NET; NET1; SLC6A2; SLC6A5

          View more View less

          UniProt ID: (Human) P23975

          View more View less

          Entrez Gene ID: (Human) 6530

          View more View less

          Function(s)
          dopamine:sodium symporter activity norepinephrine:sodium symporter activity protein binding monoamine transmembrane transporter activity metal ion binding primary active transporter
          Process(es)
          transport chemical synaptic transmission monoamine transport norepinephrine transport response to pain dopamine uptake involved in synaptic transmission transmembrane transport
          It has to be done as per old AB suggested Products section.

          Disclaimer

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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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