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Invitrogen
SLC6A20 Polyclonal Antibody
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FIGURE: 1 / 3
SLC6A20 Antibody (PA5-68332) in WB
EMBO molecular medicine 2021 -
5 Figure Knockdown of SLC6A20A expression by antisense oligonucleotide increases whole-brain glycine levels and NMDAR function and rescues repetitive climbing in Pten DeltaC / DeltaC mice Schematic representation for the intracerebroventricular (ICV) injection of Slc6a20a antisense oligonucleotide (ASO) into the lateral ventricle (LV) for the reduction of Slc6a20a expression in the whole mouse brain. Slc6a2... View More
Product Details
PA5-68332
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Published species
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthesized peptide derived from human SLC6A20.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Predicted to react with Mouse samples.
Target Information
Mediates the calcium-dependent uptake of imino acids such as L-proline, N-methyl-L-proline and pipecolate as well as N-methylated amino acids. Involved in the transport of glycine.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: IMINO-B; neurotransmitter transporter RB21A; orphan transporter XT3; slc6a20a; Sodium- and chloride-dependent transporter XTRP3; Sodium- and chloride-dependent transporter XTRP3A; sodium-dependent imino acid transporter 1; Sodium/imino-acid transporter 1; solute carrier family 6 (neurotransmitter transporter), member 20; solute carrier family 6 (proline IMINO transporter), member 20; Solute carrier family 6 member 20; Solute carrier family 6 member 20A; Transporter rB21A homolog; X transporter protein 3; X transporter protein 3 similar 1
Gene Aliases: A730081N20Rik; AU022428; IMINO; SIT1; SLC6A20; Slc6a20a; XT3; Xt3s1; Xtm3s1; XTRP3; Xtrp3s1
UniProt ID: (Human) Q9NP91, (Mouse) Q8VDB9
Entrez Gene ID: (Human) 54716, (Mouse) 102680
proline:sodium symporter activity
protein binding
amino acid transmembrane transporter activity
neutral amino acid transmembrane transporter activity
L-isoleucine transmembrane transporter activity
L-proline transmembrane transporter activity
amino-acid betaine transmembrane transporter activity
symporter activity
solute:sodium symporter activity
transmembrane transporter activity
neurotransmitter:sodium symporter activity
primary active transporter
amino acid transport
glycine transport
proline transport
amino-acid betaine transport
sodium ion transmembrane transport
amino acid import across plasma membrane
transport across blood-brain barrier
glycine import across plasma membrane
L-isoleucine import across plasma membrane
L-proline import across plasma membrane
proline import across plasma membrane
amino acid transmembrane transport
transport
neurotransmitter transport
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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