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Invitrogen
SLC7A1 Polyclonal Antibody
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FIGURE: 1 / 2
SLC7A1 Antibody (PA5-114947) in IHC (P)
Immunohistochemistry analysis of SLC7A1 in human liver cancer and adjacent normal tissues. Samples were treated with formaldehyde and treated with citrate buffer for antigen retrieval, blocked, and incubated (1.5 hours at 22°C) with polyclonal antibody (Product # PA5-114947) at a dilution of 1:100. Secondary staining was applied with HRP conjugated anti-Rabbit.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-114947
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human SLC7A1(Accession P30825), corresponding to amino acid residues S464-T514.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antibody detects endogenous levels of total CAT1.
Target Information
SLC7A1 is a high-affinity, low capacity permease involved in the transport of the cationic amino acids (arginine, lysine and ornithine) in non-hepatic tissues. It may also function as an ecotropic retroviral leukemia receptor.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: amino acid transporter, cationic 1; CAT-1; CAT1; cationic amino acid transporter 1; cationic amino acid transporter, y+ system; cationinc amino acid transporter 1; Ecotropic retroviral leukemia receptor; Ecotropic retroviral leukemia receptor homolog; ecotropic retroviral receptor; Ecotropic retrovirus receptor; Ecotropic retrovirus receptor homolog; ERR; High affinity cationic amino acid transporter 1; REC1L; solute carrier family 7 (cationic amino acid transporter, y+ system), member 1; Solute carrier family 7 member 1; Solute carrier family 7 member A1 (amino acid transporter cationic 1); solute carrier family 7, member 1; System Y+ basic amino acid transporter; transport system y+; unnamed protein product
Gene Aliases: 4831426K01Rik; AI447493; Atrc-1; ATRC1; CAT-1; CAT1; ERR; HCAT1; mCAT-1; Rec-1; REC1L; Rev-1; SLC7A1
UniProt ID: (Human) P30825, (Mouse) Q09143
Entrez Gene ID: (Human) 6541, (Mouse) 11987, (Rat) 25648
L-ornithine transmembrane transporter activity
virus receptor activity
L-histidine transmembrane transporter activity
protein binding
amino acid transmembrane transporter activity
basic amino acid transmembrane transporter activity
L-lysine transmembrane transporter activity
transmembrane transporter activity
L-arginine transmembrane transporter activity
arginine transmembrane transporter activity
antiporter activity
amino acid transporter
amino acid transport
L-amino acid transport
lysine transport
ornithine transport
positive regulation of T cell proliferation
viral entry into host cell
transmembrane transport
amino acid import across plasma membrane
L-arginine import across plasma membrane
transport across blood-brain barrier
L-ornithine transmembrane transport
L-lysine transmembrane transport
L-histidine import across plasma membrane
arginine transmembrane transport
amino acid transmembrane transport
transport
arginine transport
regulation of TOR signaling
basic amino acid transport
cation transmembrane transport
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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