Positive Samples: Raji, Jurkat, 22RV1, Mouse testis, Rat brain, Rat liver; Cellular Location: Cell membrane, Multi-pass membrane protein
SLC7A1 is a high-affinity, low capacity permease involved in the transport of the cationic amino acids (arginine, lysine and ornithine) in non-hepatic tissues. It may also function as an ecotropic retroviral leukemia receptor.
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Protein Aliases: amino acid transporter, cationic 1; CAT-1; CAT1; cationic amino acid transporter 1; cationic amino acid transporter, y+ system; cationinc amino acid transporter 1; Ecotropic retroviral leukemia receptor; Ecotropic retroviral leukemia receptor homolog; ecotropic retroviral receptor; Ecotropic retrovirus receptor; Ecotropic retrovirus receptor homolog; ERR; High affinity cationic amino acid transporter 1; solute carrier family 7 (cationic amino acid transporter, y+ system), member 1; Solute carrier family 7 member 1; Solute carrier family 7 member A1 (amino acid transporter cationic 1); solute carrier family 7, member 1; System Y+ basic amino acid transporter
Gene Aliases: 4831426K01Rik; AI447493; Atrc-1; ATRC1; CAT-1; CAT1; ERR; HCAT1; mCAT-1; Rec-1; REC1L; Rev-1; SLC7A1