Immunogen sequence: FLAFLVLGLS VLTTYGVHAI TRLEAWSLAL LALFLVLFVA IVLTIWRQPQ NQQKVAFMVP FLPFLPAFSI LVNIYLMVQL SADTWVRFSI WMAIGFLIYF SYGIRHSLEG HLRDENNEED AYPDNVHAAA EEKSAIQAND HHPRNLSSPF IFHEKTSEF; Positive Samples: 293T, HepG2, HeLa, Mouse liver, Mouse brain, Rat liver; Cellular Location: Cell membrane, Multi-pass membrane protein
The protein encoded by this gene is a cationic amino acid transporter and a member of the APC (amino acid-polyamine-organocation) family of transporters. The encoded membrane protein is responsible for the cellular uptake of arginine, lysine and ornithine. Three transcript variants encoding different isoforms have been found for this gene.
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Protein Aliases: 20.5; amino acid transporter, cationic 2 (low affinity); CAT-2; Cationic amino acid transporter 2; cationic amino acid transporter 2A; cationic amino acid transporter 2B; cationic amino acid transporter-2A; Low affinity cationic amino acid transporter 2; solute carrier family 7 (cationic amino acid transporter, y+ system), member 2; Solute carrier family 7 member 2; solute carrier family 7, member 2; T-cell early activation protein; TEA
Gene Aliases: 20.5; AI158848; ATRC2; CAT-2; CAT2; Cat2a; Cat2b; HCAT2; SLC7A2; Tea
Molecular Function: amino acid transporter