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Proteintech
SLC7A6 Polyclonal Antibody
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Product Details
13823-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
SLC7A6 Fusion Protein Ag4924
Conjugate
Form
Liquid
Concentration
267 µg/mL
Amount
40.05 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
Product Specific Information
Aliquoting is unnecessary for -20°C storage.
Target Information
Involved in the sodium-independent uptake of dibasic amino acids and sodium-dependent uptake of some neutral amino acids. Requires coexpression with SLC3A2/4F2hc to mediate the uptake of arginine, leucine and glutamine. Also acts as an arginine/glutamine exchanger, following an antiport mechanism for amino acid transport, influencing arginine release in exchange for extracellular amino acids. Plays a role in nitric oxide synthesis in human umbilical vein endothelial cells (HUVECs) via transport of L-arginine. Involved in the transport of L-arginine in monocytes. Reduces uptake of ornithine in retinal pigment epithelial (RPE) cells. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: amino acid permease; Cationic amino acid transporter, y+ system; KIAA0245; slc7a6; solute carrier family 7 (amino acid transporter light chain, y+L system), member 6; solute carrier family 7 (cationic amino acid transporter, y+ system), member 6; Solute carrier family 7 member 6; solute carriersolute carrier family 7 (cationic amino acid transporter, y+ system), member 6; y(+)L-type amino acid transporter 2; Y+L amino acid transporter 2; y+LAT-2; Y+LAT2
Gene Aliases: AI643885; KIAA0245; LAT-2; LAT3; SLC7A6; y+LAT-2
UniProt ID: (Human) Q92536, (Mouse) Q8BGK6
Entrez Gene ID: (Human) 9057, (Mouse) 330836
protein binding
amino acid transmembrane transporter activity
basic amino acid transmembrane transporter activity
L-amino acid transmembrane transporter activity
antiporter activity
transmembrane transporter activity
arginine binding
L-arginine transmembrane transporter activity
L-lysine:L-arginine antiporter activity
molecular_function
transporter
amino acid transmembrane transport
nitric oxide biosynthetic process
amino acid transport
neutral amino acid transport
leucine transport
ornithine transport
glycine betaine transport
transmembrane transport
L-lysine transmembrane transport
arginine transmembrane transport
transport
L-alpha-amino acid transmembrane transport
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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