Peptide sequence: WGTLVQDIFT YAKVLALIAV IVAGIVRLGQ GASTHFENSF EGSSFAVGDI
Sequence homology: Cow: 100%; Dog: 86%; Guinea Pig: 79%; Horse: 100%; Human: 100%; Mouse: 79%; Pig: 93%; Rabbit: 100%; Rat: 79%
The protein encoded by this gene is the light subunit of a cationic amino acid transporter. This sodium-independent transporter is formed when the light subunit encoded by this gene dimerizes with the heavy subunit transporter protein SLC3A2. This transporter is found in epithelial cell membranes where it transfers cationic and large neutral amino acids from the cell to the extracellular space. Defects in this gene are a cause of lysinuric protein intolerance (LPI). Several transcript variants encoding the same protein have been found for this gene.
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Protein Aliases: amino acid transporter SLC7A7 y+LAT1; Monocyte amino acid permease 2; MOP-2; solute carrier family 7 (amino acid transporter light chain, y+L system), member 7; solute carrier family 7 (cationic amino acid transporter, y+ system), member 7; Solute carrier family 7 member 7; solute carrier family 7 member 7-like; y(+)L-type amino acid transporter 1; Y+L amino acid transporter 1; y+LAT-1; Y+LAT1
Gene Aliases: AI790233; BOS_10153; LAT3; LPI; MOP-2; my+lat1; SLC7A7; y+LAT-1; Y+LAT1