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| Applications | Tested Dilution | Publications |
|---|---|---|
Western Blot (WB) |
1:200 | - |
Immunohistochemistry (Frozen) (IHC (F)) |
1:200 | - |
Immunocytochemistry (ICC/IF) |
Assay-dependent | - |
| Product Specifications | |
|---|---|
Species Reactivity |
Human, Mouse, Rat |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
Peptide corresponding to amino acid residues 515-528 of human NHE-6 (Intracellular, C-terminus) |
Conjugate |
Unconjugated |
Form |
Lyophilized |
Concentration |
0.8 mg/mL |
Purification |
Antigen affinity chromatography |
Storage buffer |
PBS, pH 7.4, with 1% BSA |
Contains |
0.05% sodium azide |
Storage conditions |
-20°C |
RRID |
AB_2857284 |
Reconstitute antibody with 50 µL of double distilled water (DDW). The reconstituted solution can be stored at 4 degrees C for up to 1 week. For longer periods, small aliquots should be stored at -20 degrees C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
Peptide sequence is: (C)EHLGVPE NERRTTK
Homology: Mouse, rat - 13/14 amino acid residues identical.
Na+/H+ exchangers-1-6 (Na+/H+ antiporters, NHE-1-6) are integral membrane proteins that are expressed in most mammalian tissues where they regulate intracellular pH and cell volume. NHEs mediate the secondary active extrusion of hydrogen (H+) ions out of cells in exchange for extracellular sodium (Na+). Excluding NHE-1, which is ubiquitously expressed, the NHE isoforms 2-6 have distinct tissue- and cell type-dependent expression, and inhibitiory characteristics by amiloride analogs.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Na(+)/H(+) exchanger 6; NHE-6; Sodium/hydrogen exchanger 6; solute carrier family 9 (sodium/hydrogen exchanger), isoform 6; solute carrier family 9 (sodium/hydrogen exchanger), member 6; Solute carrier family 9 member 6; solute carrier family 9, subfamily A (NHE6, cation proton antiporter 6), member 6
Gene Aliases: 3732426M05; 6430520C02Rik; KIAA0267; mKIAA0267; MRSA; NHE6; RGD1563582; SLC9A6
UniProt ID: (Human) Q5JPP8
Entrez Gene ID: (Human) 10479, (Rat) 302863, (Mouse) 236794
Molecular Function:
transporter
secondary carrier transporter
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