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Product Details
PA5-63725
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human SLC9A6. Recombinant protein control fragment (Product #RP-101961).
Conjugate
Form
Liquid
Concentration
0.05 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2647573
Product Specific Information
Immunogen sequence: PRRFMGNSSE DALDRELAFG DHELVIRGTR LVLPMDDSEP PLNLLDNTRH G
Highest antigen sequence identity to the following orthologs: Mouse - 90%, Rat - 86%.
Target Information
Na+/H+ exchangers-1-6 (Na+/H+ antiporters, NHE-1-6) are integral membrane proteins that are expressed in most mammalian tissues where they regulate intracellular pH and cell volume. NHEs mediate the secondary active extrusion of hydrogen (H+) ions out of cells in exchange for extracellular sodium (Na+). Excluding NHE-1, which is ubiquitously expressed, the NHE isoforms 2-6 have distinct tissue- and cell type-dependent expression, and inhibitiory characteristics by amiloride analogs.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Na(+)/H(+) exchanger 6; NHE-6; Sodium/hydrogen exchanger 6; solute carrier family 9 (sodium/hydrogen exchanger), member 6; Solute carrier family 9 member 6; solute carrier family 9, subfamily A (NHE6, cation proton antiporter 6), member 6
Gene Aliases: KIAA0267; MRSA; NHE6; SLC9A6
UniProt ID: (Human) Q92581
Entrez Gene ID: (Human) 10479
transport
ion transport
brain-derived neurotrophic factor receptor signaling pathway
axon extension
neuron projection morphogenesis
synapse organization
regulation of neurotrophin TRK receptor signaling pathway
regulation of intracellular pH
dendritic spine development
potassium ion transmembrane transport
dendrite extension
sodium ion import across plasma membrane
hydrogen ion transmembrane transport
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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