Peptide sequence: AKYLNPFFTR RLTQEDLHHG RIQMKTLTNK WYEEVRQGPS GSEDDEQELL
Sequence homology: Cow: 93%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 93%
Sodium-hydrogen exchangers (NHEs), such as SLC9A8, are integral transmembrane proteins that exchange extracellular Na+ for intracellular H+. NHEs have multiple functions, including intracellular pH homeostasis, cell volume regulation, and electroneutral NaCl absorption in epithelia (Xu et al., 2008).
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Protein Aliases: DKFZp686C03237; FLJ42500; MGC138418; Na(+)/H(+) exchanger 8; NHE-8; NHE-8 antibody; SLC9A8 antibody; Sodium/hydrogen exchanger 8; solute carrier family 9 (sodium/hydrogen exchanger), isoform 8; solute carrier family 9 (sodium/hydrogen exchanger), member 8; Solute carrier family 9 member 8; solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
Gene Aliases: KIAA0939; NHE-8; NHE8; SLC9A8
UniProt ID: (Human) Q9Y2E8
Entrez Gene ID: (Human) 23315