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Product Details
24584-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Published species
Not Applicable
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
SLCO4C1 Fusion Protein Ag20177 (1-105 aa encoded by BC152989)
Conjugate
Form
Liquid
Concentration
0.21 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MKSAKGIEN LAFVPSSPDI LRRLSASPSQ IEVSALSSDP QRENSQPQEL QKPQEPQKSP EPSLPSAPPN VSEEKLRSLS LSEFEEGSYG WRNFHPQCLQ RCNTPG (1-105 aa encoded by B C152989)
Target Information
Organic anion transporter, capable of transporting pharmacological substances such as digoxin, ouabain, thyroxine, methotrexate and cAMP. May participate in the regulation of membrane transport of ouabain. Involved in the uptake of the dipeptidyl peptidase-4 inhibitor sitagliptin and hence may play a role in its transport into and out of renal proximal tubule cells. May be involved in the first step of the transport pathway of digoxin and various compounds into the urine in the kidney. May be involved in sperm maturation by enabling directed movement of organic anions and compounds within or between cells. This ion- transporting process is important to maintain the strict epididymal homeostasis necessary for sperm maturation. May have a role in secretory functions since seminal vesicle epithelial cells are assumed to secrete proteins involved in decapacitation by modifying surface proteins to facilitate the acquisition of the ability to fertilize the egg.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: OATP-H; OATP-M1; Oatp-R; OATP4C1; Organic anion transporter M1; Organic anion transporting polypeptide 4C1; SLCO4C1; Solute carrier family 21 member 20; Solute carrier organic anion transporter family member 4C1; solute carrier organic anion transporter family, member 4C1
Gene Aliases: 9530051F04; C330017E21Rik; OATP-H; OATP-M1; oatp-R; OATP4C1; OATPX; PRO2176; SLC21A20; SLCO4C1
UniProt ID: (Human) Q6ZQN7, (Mouse) Q8BGD4
Entrez Gene ID: (Human) 353189, (Mouse) 227394
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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