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Invitrogen
SLIRP Polyclonal Antibody
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FIGURE: 1 / 5
SLIRP Antibody (PA1-46148) in ICC/IF
Immunocytochemistry analysis of SLIRP in HeLa cells. Samples were incubated with SLIRP polyclonal antibody (Product # PA1-46148) using a dilution of 1:200 dilution overnight at 4°C followed by anti-rabbit Dylight 488 (Green) at a dilution of 1:500. Cells were fixed for 10 minutes using 10% formalin and then permeabilized for 5 minutes using 1X TBS + 0.5% Triton-X100. Alpha tubulin was used as a co-stain at a 1:1,000 dilution and detected with and anti-mouse Dylight 550 (Red) at a 1:500 dilution. Nuclei were counterstained with DAPI (Blue).... View More
Product Details
PA1-46148
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Non-human primate
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide made to a C-terminal region of human SLIRP protein.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS
Contains
0.05% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Prior to immunostaining paraffin tissues, antigen retrieval with sodium citrate buffer (pH 6.0) is recommended.
Suggested positive control: antigen standard for C14orf156 (transient overexpression lysate), human liver protein.
Target Information
SLIRP (SRA stem-loop interacting RNA binding protein) is expressed in normal and tumor tissues, but the majority of the endogenous SLIRP resides in the mitochondria. SLIRP may regulate mitochondrial functions and has the potential to shut down estrogen in breast cancer cells and testosterone in prostate cancer cells. SLIRP has also been shown to turn down genes involved in energy metabolism.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: SRA stem-loop-interacting RNA-binding protein, mitochondrial
Gene Aliases: 1810035L17Rik; C14orf156; DC23; DC50; PD04872; SLIRP
UniProt ID: (Human) Q9GZT3, (Mouse) Q9D8T7
Entrez Gene ID: (Human) 81892, (Mouse) 380773
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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