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Proteintech
SLITRK6 Polyclonal Antibody
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Product Details
21150-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
SLITRK6 Fusion Protein Ag15701 (621-816 aa encoded by BC101070)
Conjugate
Form
Liquid
Concentration
0.35 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: IVFCAAGIV VLVLHRRRRY KKKQVDEQMR DNSPVHLQYS MYGHKTTHHT TERPSASLYE QHMVSPMVHV YRSPSFGPKH LEEEEERNEK EGSDAKHLQR SLLEQENHSP LTGSNMKYKT TNQSTEFLSF QDASSLYRNI LEKERELQQL GITEYLRKNI AQLQPDMEAH YPGAHEELKL METLMYSRPR KVLVEQT (621-816 aa encoded by BC101070 )
Target Information
SLIT and NTRK-like family 6 (Slitrk6) is a member a protein family consisting of six homologous transmembrane proteins (Slitrk1-6) that share two conserved leucine-rich repeat domains in the extracellular domain and have significant homology to Slit, a secreted axonal growth-controlling protein. These proteins are also homologous to trk neurotrophin receptors in their intracellular domains. Expression of Slitrk proteins is highly restricted to neural and brain tumor tissues, but varies within the protein family. Slitrk6 expression has been observed in tissues such as tongue, lung, gastrointestinal tract, and pancreas. Like every other Slitrk protein except Slitrk1, overexpression of Slitrk6 inhibited neurite outgrowth in cultured neurons, suggesting that these proteins are involved in the control of neurite outgrowth. At least two isoforms of Slitrk6 are known to exisit.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 4832410J21Rik; neuronal transmembrane protein Slitrk6; RP11-272M24.2; SLIT and NTRK-like family, member 6; SLIT and NTRK-like protein 6; slit and trk like gene 6
Gene Aliases: 4832410J21Rik; DFNMYP; SLITRK6; Sltk6
UniProt ID: (Human) Q9H5Y7, (Mouse) Q8C110
Entrez Gene ID: (Human) 84189, (Mouse) 239250, (Rat) 290467
startle response
lens development in camera-type eye
auditory receptor cell morphogenesis
axonogenesis
synapse assembly
visual perception
sensory perception of sound
adult locomotory behavior
vestibulocochlear nerve development
auditory behavior
multicellular organism growth
inner ear morphogenesis
camera-type eye development
neuron projection morphogenesis
response to stimulus
positive regulation of synapse assembly
vestibular reflex
linear vestibuloocular reflex
innervation
cochlea development
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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