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Invitrogen
SLPI Polyclonal Antibody
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Product Details
PA5-20385
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A 17 amino acid peptide from near the center of human SLPI.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS
Contains
0.02% sodium azide
Storage conditions
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
A suggested positive control is Daudi cell lysate.
PA5-20385 can be used with blocking peptide PEP-0502.
Target Information
SLPI is a secreted inhibitor which protects epithelial tissues from serine proteases. It is found in various secretions including seminal plasma, cervical mucus, and bronchial secretions, and has affinity for trypsin, leukocyte elastase, and cathepsin G. Its inhibitory effect contributes to the immune response by protecting epithelial surfaces from attack by endogenous proteolytic enzymes; the protein is also thought to have broad-spectrum anti-biotic activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: ALP; Antileukoproteinase; BLPI; HUSI-1; MPI; Mucus proteinase inhibitor; Protease inhibitor WAP4; RP23-462O16.7; Secretory leukocyte protease inhibitor; secretory leukocyte protease inhibitor (antileukoproteinase); Seminal proteinase inhibitor; SLPI; unnamed protein product; WAP four-disulfide core domain protein 4
Gene Aliases: ALK1; ALP; BLPI; HUSI; HUSI-I; MPI; SLPI; WAP4; WFDC4
UniProt ID: (Human) P03973, (Mouse) P97430
Entrez Gene ID: (Human) 6590, (Mouse) 20568
immune system process
immune response
antibacterial humoral response
negative regulation of protein binding
response to lipopolysaccharide
defense response to bacterium
negative regulation of viral genome replication
innate immune response
host-mediated perturbation of symbiont process
negative regulation of peptidase activity
negative regulation of endopeptidase activity
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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