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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • SLX1 Antibodies

          Invitrogen

          SLX1A Polyclonal Antibody

          View all (4) SLX1 antibodies

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          Cite SLX1A Polyclonal Antibody

          • Antibody Testing Data (2)
          SLX1A Antibody in Immunocytochemistry (ICC/IF)
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          SLX1A Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.

          FIGURE: 1 / 2

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          SLX1A Antibody (PA5-61410) in ICC/IF

          Immunofluorescent staining of SLX1B in human cell line A549 using a SLX1B Polyclonal Antibody (Product # PA5-61410) shows localization to nucleoplasm. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          SLX1A Antibody in Immunocytochemistry (ICC/IF)
          SLX1A Antibody in Immunohistochemistry (IHC)

          Product Details

          PA5-61410

          Applications
          Tested Dilution
          Publications

          Immunohistochemistry (Paraffin) (IHC (P))

          1:200-1:500
          -

          Immunocytochemistry (ICC/IF)

          0.25-2 µg/mL
          -
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Recombinant protein fragment of Human SLX1A. Recombinant protein control fragment (Product #RP-104420).

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.2 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.2, with 40% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2647601

          Product Specific Information

          Immunogen sequence: PGCLLRAHVI CLAEEFLQEE PGQLLPLEGQ CPCCEKSLLW GDLIWLCQMD TEKEVEDSEL EEAHWTDLLE T

          Highest antigen sequence identity to the following orthologs: Mouse - 79%, Rat - 77%.

          Target Information

          SLX1 encodes a protein that is an important regulator of genome stability. The protein represents the catalytic subunit of the SLX1-SLX4 structure-specific endonuclease, which can resolve DNA secondary structures that are formed during repair and recombination processes. Two identical copies of this gene are located on the p arm of chromosome 16 due to a segmental duplication. SLZ1A represents the more centromeric copy and SLZ1B represents the more telomeric copy.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Let us know so we can reference it here.
          Cite this product

          Bioinformatics

          Protein Aliases: GIY-YIG domain-containing protein 1; SLX1 structure-specific endonuclease subunit homolog A; SLX1 structure-specific endonuclease subunit homolog B; SLX1A; SLX1B; Structure-specific endonuclease subunit SLX1

          View more View less

          Gene Aliases: GIYD1; GIYD2; SLX1; SLX1A; SLX1B

          View more View less

          UniProt ID: (Human) Q9BQ83

          View more View less

          Entrez Gene ID: (Human) 548593, (Human) 79008

          View more View less

          Function(s)
          endodeoxyribonuclease activity protein binding crossover junction endodeoxyribonuclease activity 5'-flap endonuclease activity metal ion binding endodeoxyribonuclease
          Process(es)
          double-strand break repair via homologous recombination DNA repair DNA double-strand break processing involved in repair via single-strand annealing interstrand cross-link repair nucleic acid phosphodiester bond hydrolysis t-circle formation positive regulation of t-circle formation
          It has to be done as per old AB suggested Products section.
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          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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