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Invitrogen
SLX1B Polyclonal Antibody
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Product Details
PA5-46622
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide directed towards the C-terminal of human SLX1B (aa 222-271).
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Amount
50 µg
Purification
Affinity Chromatography
Storage buffer
PBS with 2% sucrose
Contains
0.09% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Peptide sequence: QEEPGQLLPL EGQCPCCEKS LLWGDLIWLC QMDTEKEVED SELEEAHWTD
Sequence homology: Horse: 90%; Human: 100%; Yeast: 79%
Target Information
SLX1 encodes a protein that is an important regulator of genome stability. The protein represents the catalytic subunit of the SLX1-SLX4 structure-specific endonuclease, which can resolve DNA secondary structures that are formed during repair and recombination processes. Two identical copies of this gene are located on the p arm of chromosome 16 due to a segmental duplication. SLZ1A represents the more centromeric copy and SLZ1B represents the more telomeric copy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: GIY-YIG domain-containing protein 1; SLX1 structure-specific endonuclease subunit homolog A; SLX1 structure-specific endonuclease subunit homolog B; SLX1A; SLX1B; Structure-specific endonuclease subunit SLX1; unnamed protein product
Gene Aliases: GIYD1; GIYD2; SLX1; SLX1A; SLX1B
UniProt ID: (Human) Q9BQ83
Entrez Gene ID: (Human) 548593, (Human) 79008
double-strand break repair via homologous recombination
DNA repair
DNA recombination
cellular response to DNA damage stimulus
DNA double-strand break processing involved in repair via single-strand annealing
telomere maintenance via telomere lengthening
regulation of telomere maintenance
telomeric D-loop disassembly
t-circle formation
negative regulation of telomere maintenance via telomere lengthening
positive regulation of t-circle formation
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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