This Antibody was verified by IP Mass Spectrometry to ensure that the antibody binds to the antigen stated. View Details
This antibody is predicted to react with mouse and rat based on sequence homology.
SMAD4 is the common SMAD (co-SMAD)mediator of signal transduction by TGF-beta (transforming growth factor). It promotes binding of the SMAD2/SMAD4/FAST-1 complex to DNA and provides an activation function required for SMAD1 or SMAD2 to stimulate transcription. It may act as a tumor suppressor.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: deleted in pancreatic carcinoma locus 4; Deletion target in pancreatic carcinoma 4; DPC4; hSMAD4; MAD homolog 4; MADH4; Mothers against decapentaplegic homolog 4; mothers against decapentaplegic, Drosophila, homolog of, 4; Mothers against DPP homolog 4; SMAD 4; SMAD family member 4; SMAD, mothers against DPP homolog 4; SMAD4
Gene Aliases: DPC4; JIP; MADH4; MYHRS; SMAD4
UniProt ID: (Human) Q13485
Entrez Gene ID: (Human) 4089