This antibody is predicted to react with mouse based on sequence homology.
SMAD6 belongs to the SMAD family of proteins, which are related to Drosophila 'mothers against decapentaplegic' (Mad) and C. elegans Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein functions in the negative regulation of BMP and TGF-beta/activin-signalling.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: drosophila; 6; homolog of; hSMAD6; HsT17432; MAD homolog 6; MADH6; MADH7; Mothers against decapentaplegic; Mothers against decapentaplegic homolog 6; mothers against decapentaplegic, drosophila, homolog of, 6; mothers against DPP homolog 6; SMAD; SMAD 6; SMAD family member 6; SMAD, mothers against DPP homolog 6
Gene Aliases: AOVD2; HsT17432; MADH6; MADH7; SMAD6
UniProt ID: (Human) O43541
Entrez Gene ID: (Human) 4091
Molecular Function: transcription factor