This Antibody was verified by Knockdown to ensure that the antibody binds to the antigen stated. View Details
Immunogen sequence: SVTLLKASEV EEILDGNDEK YKAVSISTEP PTYLREQKAK RNSQWVPTLP NSSHHLDAVP CSTTINRNRM GRDKKRTFPL CFDDHDPAVI HENASQPE
Highest antigen sequence identity to the following orthologs: Mouse - 100%, Rat - 100%.
The SWI-SNF complex is involved in the activation of transcription via the remodeling of nucleosome structure in an ATP-dependent manner. Brm (also designated SNF2alpha) and Brg-1 (also designated SNF2beta) are the ATPase subunits of the mammalian SWI-SNF complex. Brm, Brg-1, Ini1 (integrase interactor 1, also designated SNF5), BAF155 (also designated SRG3) and BAF170 are thought to comprise the functional core of the SWI-SNF complex. Addition of Ini1, BAF155 and BAF170 to Brg-1 appears to increase remodeling activity. Other complex subunits are thought to play regulatory roles. hSNF2L and hSNF2H both appear to be homologs of Drosophila ISWI, a Brm related ATPase that is present in chromatin remodeling complexes other than SWI/SNF, including the NURF (nucleosome remodeling factor).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: BAF47; BRG1-associated factor 47; hSNF5; Integrase interactor 1 protein; malignant rhabdoid tumor suppressor; mSNF5; protein phosphatase 1, regulatory subunit 144; SNF5 homolog; sucrose nonfermenting, yeast, homolog-like 1; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1; SWI/SNF-related matrix-associated protein; SWI10; TYE4
Gene Aliases: AU020204; BAF47; CSS3; hSNFS; INI1; MRD15; PPP1R144; RDT; RTPS1; Sfh1p; SMARCB1; SNF5; SNF5/INI1; SNF5L1; Snr1; SWNTS1