Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Product Details
17722-1-AP
| Applications | Tested Dilution | Publications |
|---|---|---|
Western Blot (WB) |
1:2,000-1:16,000 | - |
Immunohistochemistry (Paraffin) (IHC (P)) |
1:20-1:200 | - |
Immunoprecipitation (IP) |
0.5-4.0 µg | - |
| Product Specifications | |
|---|---|
Species Reactivity |
Human, Mouse, Rat |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
SMARCC1 Fusion Protein Ag12109 (756-1105 aa encoded by BC050564) |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
0.3 mg/mL |
Purification |
Antigen affinity chromatography |
Storage buffer |
PBS, pH 7.3, with 50% glycerol |
Contains |
0.02% sodium azide |
Storage conditions |
-20°C |
Product Specific Information
Immunogen sequence: GLESSCIAG TGPDEPEKLE GAEEEKMEAD PDGQQPEKAE NKVENETDEG DKAQDGENEK NSEKEQDSEV SEDTKSEEKE TEENKELTDT CKERESDTGK KKVEHEISEG NVATAAAAAL ASAATKAKHL AAVEERKIKS LVALLVETQM KKLEIKLRHF EELETIMDRE KEALEQQRQQ LLTERQNFHM EQLKYAELRA RQQMEQQQHG QNPQQAHQHS GGPGLAPLGA AGHPGMMPHQ QPPPYPLMHH QMPPPHPPQP GQIPGPGSMM PGQHMPGRMI PTVAANIHPS GSGPTPPGMP PMPGNILGPR VPLTAPNGMY PPPPQQQPPP PPPADGVPPP PAPGPPASAA P (756-1105 aa encoded by BC050564)
Target Information
The protein encoded by this gene is a member of the SWI/SNF family of proteins, whose members display helicase and ATPase activities and which are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI and contains a predicted leucine zipper motif typical of many transcription factors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: BAF155; BRG1-associated factor 155; chromatin remodeling complex BAF155 subunit; mammalian chromatin remodeling complex BRG1-associated factor 155; SWI/SNF complex 155 kDa subunit; SWI/SNF complex subunit SMARCC1; SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 1; SWI3-related protein
Gene Aliases: AI115498; BAF155; CRACC1; Rsc8; SMARCC1; SRG3; SWI3
UniProt ID: (Human) Q92922, (Mouse) P97496
Entrez Gene ID: (Human) 6599, (Rat) 301020, (Mouse) 20588
Molecular Function:
chromatin/chromatin-binding, or -regulatory protein
nucleosome disassembly
chromatin remodeling
transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
nervous system development
insulin receptor signaling pathway
organ morphogenesis
covalent chromatin modification
prostate gland development
negative regulation of proteasomal ubiquitin-dependent protein catabolic process
ATP-dependent chromatin remodeling
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
DNA packaging
regulation of transcription, DNA-templated
chromatin modification
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support