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Proteintech
SMARCC1 Polyclonal Antibody
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Product Details
17722-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
SMARCC1 Fusion Protein Ag12109 (756-1105 aa encoded by BC050564)
Conjugate
Form
Liquid
Concentration
0.3 mg/mL
Amount
45 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: GLESSCIAG TGPDEPEKLE GAEEEKMEAD PDGQQPEKAE NKVENETDEG DKAQDGENEK NSEKEQDSEV SEDTKSEEKE TEENKELTDT CKERESDTGK KKVEHEISEG NVATAAAAAL ASAATKAKHL AAVEERKIKS LVALLVETQM KKLEIKLRHF EELETIMDRE KEALEQQRQQ LLTERQNFHM EQLKYAELRA RQQMEQQQHG QNPQQAHQHS GGPGLAPLGA AGHPGMMPHQ QPPPYPLMHH QMPPPHPPQP GQIPGPGSMM PGQHMPGRMI PTVAANIHPS GSGPTPPGMP PMPGNILGPR VPLTAPNGMY PPPPQQQPPP PPPADGVPPP PAPGPPASAA P (756-1105 aa encoded by BC050564)
Target Information
The protein encoded by this gene is a member of the SWI/SNF family of proteins, whose members display helicase and ATPase activities and which are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI and contains a predicted leucine zipper motif typical of many transcription factors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: BAF155; BRG1-associated factor 155; chromatin remodeling complex BAF155 subunit; mammalian chromatin remodeling complex BRG1-associated factor 155; SWI/SNF complex 155 kDa subunit; SWI/SNF complex subunit SMARCC1; SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 1; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 1; SWI3-related protein; unnamed protein product
Gene Aliases: AI115498; BAF155; CRACC1; HYC5; Rsc8; SMARCC1; SRG3; SWI3
UniProt ID: (Human) Q92922, (Mouse) P97496
Entrez Gene ID: (Human) 6599, (Rat) 301020, (Mouse) 20588
chromatin binding
transcription coactivator activity
protein binding
nucleosomal DNA binding
histone binding
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II distal enhancer sequence-specific DNA binding
molecular_function
protein N-terminus binding
DNA binding
chromatin/chromatin-binding, or -regulatory protein
chromatin organization
nucleosome disassembly
chromatin remodeling
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
nervous system development
positive regulation of cell proliferation
insulin receptor signaling pathway
organ morphogenesis
regulation of mitotic metaphase/anaphase transition
prostate gland development
negative regulation of proteasomal ubiquitin-dependent protein catabolic process
positive regulation of T cell differentiation
negative regulation of cell differentiation
positive regulation of cell differentiation
positive regulation of myoblast differentiation
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
regulation of G0 to G1 transition
positive regulation of stem cell population maintenance
regulation of G1/S transition of mitotic cell cycle
positive regulation of double-strand break repair
regulation of nucleotide-excision repair
ATP-dependent chromatin remodeling
DNA packaging
transcription, DNA-templated
chromatin modification
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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