Immunogen sequence: RLDIQEALK RPIKQKRKLR IFISNTFNPA KSDAEDGEGT VASWELRVEG RLLEDSALSK YDATKQKRKF SSFFKSLVIE LDKDLYGPDN HLVEWHRTAT TQETDGFQVK RPGDVNVRCT VLLMLDYQPP QFKLDPRLAR LLGIHTQTRP VIIQALWQYI KTHKLQDPHE REFVICDKYL QQIFESQRMK FSEIPQRLHA LLMPPEPIII NHVISVDPND QKKTACYDID VEVDDTLKTQ MNSFLLSTAS QQEIATLDNK IHETIETINQ LKTQREFMLS FARDPQGFIN DWLQSQCRDL KTMTDVVGNP EEERRAEFYF QPWAQEAVCR YFYSKVQQRR QELEQALGIR NT (126-476 aa encoded by BC009368)
The protein encoded by this gene is a member of the SWI/SNF family of proteins, whose members display helicase and ATPase activities and which are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI and has sequence similarity to the yeast Swp73 protein. Two transcript variants encoding different isoforms have been found for this gene.
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Protein Aliases: 60 kDa BRG-1/Brm-associated factor subunit A; BAF60A; BRG1-associated factor 60A; chromatin remodeling complex BAF60A subunit; mammalian chromatin remodeling complex BRG1-associated factor 60A; Protein D15KZ1; SMARCD1; SWI/SNF complex 60 kDa subunit; SWI/SNF complex 60 kDa subunit A; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1; Swp73-like protein
Gene Aliases: AA407987; BAF60A; CRACD1; D15Kz1; Rsc6p; SMARCD1
Molecular Function: chromatin/chromatin-binding, or -regulatory protein