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Proteintech
SMC2 Polyclonal Antibody
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Product Details
30707-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
SMC2 fusion protein Ag33471
Conjugate
Form
Liquid
Concentration
0.4 mg/mL
Amount
60 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
Product Specific Information
Immunogen sequence: DLMKKKRIVE NDKSKILTTI EDLDQKKNQA LNIAWQKVNK DFGSIFSTLL PGANAMLAPP EGQTVLDGLE FKVALGNTWK ENLTELSGGQ RSLVALSLIL SMLLFKPAPI YILDEVDAAL DLSHTQNIGQ MLRTHFTHSQ FIVVSLKEGM FNNANVLFKT KFVDGVSTVA RFTQCQNGKI SKEAKSKAKP PKGAHVEV
Target Information
CAP-E and CAP-C (Chromosome Associated Protein-E & C) are also SMC (Structural Maintenance of Chromosome) family members that form a heterodimeric complex required for mitotic chromosome condensation to achieve proper segregation of genetic information during subsequent cell division. hCAP-C/hCAP-E is a component of a multiprotein complex called condensin that interacts with phosphorylation of Histone H3 resulting in the mitotic chromosome condensation. The distribution patterns of the two heterodimeric complexes in interphase nucleus indicate independent behavior of the two complexes during cell cycle. These results suggest that the two distinct complexes are involved in different aspects of mitotic chromosome organization in humar cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CAP E; Chromosome-associated protein E; FLJ10093; hCAP-E; heterodimeric coiled-coil protein required for mitotic chromosome condensation; similar to X. laevis mitotic chromosome condensation protein XCAP-E, encoded by GenBank Accession Number U13674; SMC protein 2; SMC2 (structural maintenance of chromosomes 2, yeast)-like 1; SMC2 protein; structural maintenance of chromosomal proteins; hCAP-E; structural maintenance of chromosomes (SMC) family member; structural maintenance of chromosomes (SMC) family member, chromosome-associated protein E; Structural maintenance of chromosomes protein 2; unnamed protein product; XCAP-E homolog
Gene Aliases: CAP-E; CAPE; PRO0324; SMC-2; SMC2; SMC2L1
UniProt ID: (Human) O95347
Entrez Gene ID: (Human) 10592
nuclear division
mitotic chromosome condensation
meiotic chromosome condensation
chromosome condensation
meiotic chromosome segregation
chromosome organization
cell division
kinetochore organization
positive regulation of chromosome segregation
nuclear chromosome segregation
positive regulation of chromosome separation
positive regulation of chromosome condensation
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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